SCHEMBL9312975

SCHEMBL9312975

CCOC(=O)N1c2ccccc2CCCCc2ccccc21

nearest known ligand 0.58

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.58
KMT2A Q03164 6/20 0.56
LMNA P02545 3/20 0.56
MEN1 O00255 3/20 0.56
KDM4E B2RXH2 1/20 0.54
MAPT P10636 3/20 0.52
ALDH1A1 P00352 2/20 0.51
NOTUM Q6P988 2/20 0.51
HSD17B10 Q99714 1/20 0.51
NPSR1 Q6W5P4 1/20 0.50
NPC1 O15118 1/20 0.49
MITF O75030 1/20 0.49
RAB9A P51151 1/20 0.49
TSHR P16473 2/20 0.48
GAA P10253 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
NR1I3 Q14994 2/20 0.47
USP2 O75604 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8436386 0.93 KMT2A (0.62) BCHEKMT2ALMNAMEN1KDM4E
SCHEMBL5962488 0.87 BCHE (0.61) BCHEKMT2ALMNAMEN1KDM4E
SCHEMBL2698571 0.82 BCHE (0.73) BCHELMNAMAPTALDH1A1TSHR
SCHEMBL2322460 0.82 BCHE (0.73) BCHELMNAMAPTALDH1A1TSHR
SCHEMBL9208129 0.82 NOTUM (0.57) KMT2AMEN1ALDH1A1NOTUMNPC1
SCHEMBL5426108 0.81 NOTUM (0.65) KMT2AMEN1MAPTALDH1A1NOTUM
SCHEMBL8195655 0.81 NOTUM (0.55) KMT2ALMNAMEN1KDM4EMAPT
SCHEMBL8436410 0.80 KDM4E (0.55) BCHEKMT2ALMNAMEN1KDM4E
SCHEMBL11980498 0.79 NOTUM (0.64) BCHEKMT2ALMNAMEN1KDM4E
SCHEMBL20073949 0.78 KMT2A (0.46) BCHEKMT2ALMNAMEN1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5294484-A Multilayer element SONY CORPORATION (JP) 1994-03-15 US disclosed