SCHEMBL5962896

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL25039321	1.00	POLB (0.51)	POLBHTTNPC1CYP3A4PKM
	SCHEMBL30232098	1.00	POLB (0.51)	POLBHTTNPC1CYP3A4PKM
	SCHEMBL28788962	0.94	POLB (0.52)	POLBHTTNPC1CYP3A4PKM
	SCHEMBL2149235	0.92	HTT (0.55)	POLBHTTNPC1CYP3A4PKM
	SCHEMBL14705129	0.92	HTT (0.55)	POLBHTTNPC1CYP3A4PKM
	SCHEMBL5964493	0.91	POLB (0.54)	POLBHTTNPC1CYP3A4PKM
	SCHEMBL1012270	0.89	POLB (0.52)	POLBHTTNPC1CYP3A4PKM
	SCHEMBL14418100	0.89	HTT (0.55)	POLBHTTNPC1CYP3A4PKM
	SCHEMBL28400061	0.89	POLB (0.52)	POLBHTTNPC1CYP3A4PKM
	SCHEMBL1011872	0.89	POLB (0.52)	POLBHTTNPC1CYP3A4PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.