SCHEMBL596305

SCHEMBL596305

Cc1c[c]ccc1C(Cl)(Cl)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6918917 0.79 GABRA1 (0.35)
SCHEMBL454798 0.77 AR (0.31)
SCHEMBL697788 0.74
SCHEMBL19356874 0.74
SCHEMBL3031821 0.73
SCHEMBL4428919 0.72 SMN1; SMN2 (0.42)
SCHEMBL3028540 0.72 GABRA1 (0.31)
SCHEMBL58209 0.72
SCHEMBL5928972 0.70 TSHR (0.38)
Hydrochloric Acid SCHEMBL29140292 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8114886-B2 Pyridylmethylsulfone derivative DAIICHI SANKYO COMPANY, LIMITED (JP) 2012-02-14 US disclosed
US-20090149439-A1 PYRIDYLMETHYSULFONE DERIVATIVE DAIICHI SANKYO COMPANY LIMITED (JP) 2009-06-11 US disclosed
EP-1867636-A1 PYRIDYLMETHYLSULFONE DERIVATIVE Daiichi Sankyo Company, Limited (JP) 2007-12-19 EP disclosed
US-6048991-A Preparation of epoxides BASF AKTIENGESELLSCHAFT (DE) 2000-04-11 US disclosed
US-5916430-A Preparation of epoxides BASF AKTIENGESELLSCHAFT (DE) 1999-06-29 US disclosed
EP-0457139-B1 Process for the preparation of N-substituted imidazoles BASF AG (DE) 1996-01-24 EP disclosed
EP-0460451-B1 Process for the preparation of alpha-hydroxymethyl-ketals BASF AG (DE) 1995-05-10 EP disclosed
EP-0328955-B1 Process for the preparation of imidazole-2-carboxylic acids BASF AG (DE) 1995-05-03 EP disclosed
EP-0485783-B1 Process for producing epoxy compounds BASF AG (DE) 1995-01-11 EP disclosed
US-5266171-A Electrochemical oxidation in and etherification BASF AKTIENGESELLSCHAFT (DE) 1993-11-30 US disclosed
US-5179210-A PREPARATION OF N-SUBSTITUTED IMIDAZOLES BASF AKTIENGESELLSCHAFT (DE) 1993-01-12 US disclosed
US-5159117-A Reacting ketone or aldehyde with nitrites in presence of acid catalyst BASF AKTIENGESELLSCHAFT (DE) 1992-10-27 US disclosed
US-5117004-A Carboxylation with carbon dioxide BASF AKTIENGESELLSCHAFT (DE) 1992-05-26 US disclosed
EP-0485783-A2 Process for producing epoxy compounds BASF Aktiengesellschaft (DE) 1992-05-20 EP disclosed
EP-0472118-A1 Process for production of alpha,alpha-dialkoxycetones BASF Aktiengesellschaft (DE) 1992-02-26 EP disclosed
EP-0460451-A1 Process for the preparation of alpha-hydroxymethyl-ketals BASF Aktiengesellschaft (DE) 1991-12-11 EP disclosed
EP-0457139-A2 Process for the preparation of N-substituted imidazoles BASF Aktiengesellschaft (DE) 1991-11-21 EP disclosed
EP-0328955-A2 Process for the preparation of imidazole-2-carboxylic acids BASF Aktiengesellschaft (DE) 1989-08-23 EP disclosed