Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MPO | P05164 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.43 |
| ▸ | NLN | Q9BYT8 | 2/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 2/20 | 0.40 |
| ▸ | NOS1 | P29475 | 2/20 | 0.40 |
| ▸ | NOS2 | P35228 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Histidine SCHEMBL29086897 | 0.87 | SLC7A5 (0.47) | MAPTKDM4EMEN1LMNAMPO | |
| Pyrene SCHEMBL28913773 | 0.84 | CYP1A2 (0.43) | MAPTKDM4EMEN1LMNAMPO | |
| SCHEMBL29397866 | 0.83 | CTNNB1 (0.59) | MAPTKDM4EMEN1LMNAMPO | |
| SCHEMBL29397858 | 0.83 | CTNNB1 (0.59) | MAPTKDM4EMEN1LMNAMPO | |
| SCHEMBL93515 | 0.83 | CTNNB1 (0.59) | MAPTKDM4EMEN1LMNAMPO | |
| SCHEMBL660499 | 0.83 | CTNNB1 (0.59) | MAPTKDM4EMEN1LMNAMPO | |
| SCHEMBL93516 | 0.83 | CTNNB1 (0.59) | MAPTKDM4EMEN1LMNAMPO | |
| SCHEMBL29482763 | 0.83 | CTNNB1 (0.59) | MAPTKDM4EMEN1LMNAMPO | |
| Histidine SCHEMBL2804663 | 0.83 | CYP3A4 (0.46) | MAPTKDM4EMEN1LMNAMPO | |
| Histidine SCHEMBL28098393 | 0.83 | CYP1A2 (0.49) | MAPTKDM4EMEN1LMNAMPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7026282-B1 | Peptide antagonists of the human urokinase receptor and method for selecting them | Cancerforskningsfonden AF 1989 (Fonden Til Fremme AF Exsperimentel Cancerforskning) (DK) | 2006-04-11 | — | — | US | claimed |