Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | KLK7 | P49862 | 6/20 | 0.42 |
| ▸ | RORC | P51449 | 2/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | KLK5 | Q9Y337 | 5/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.39 |
| ▸ | RXRA | P19793 | 2/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.38 |
| ▸ | STS | P08842 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14050230 | 1.00 | ELANE (0.44) | ELANEABCB1KLK7RORCGPR119 | |
| SCHEMBL16237822 | 1.00 | ELANE (0.44) | ELANEABCB1KLK7RORCGPR119 | |
| SCHEMBL9924398 | 0.85 | ELANE (0.44) | ELANEABCB1KLK7RORCGPR119 | |
| SCHEMBL14199221 | 0.85 | ELANE (0.44) | ELANEABCB1KLK7RORCGPR119 | |
| SCHEMBL5963538 | 0.83 | ELANE (0.51) | ELANEABCB1 | |
| SCHEMBL8952612 | 0.83 | ABCB1 (0.47) | ELANEABCB1KLK7RORCGPR119 | |
| SCHEMBL7735385 | 0.83 | ABCB1 (0.47) | ELANEABCB1KLK7RORCGPR119 | |
| SCHEMBL8952629 | 0.83 | ABCB1 (0.47) | ELANEABCB1KLK7RORCGPR119 | |
| SCHEMBL8952619 | 0.83 | ABCB1 (0.47) | ELANEABCB1KLK7RORCGPR119 | |
| SCHEMBL4961152 | 0.81 | ABCB1 (0.43) | ELANEABCB1KLK7RORCGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9567312-B2 | Cabazitaxel, related compounds and methods of synthesis | SHANGHAI BIOMAN PHARMA LTD (CN) | 2017-02-14 | — | — | US | disclosed |
| US-8658811-B2 | Process for the preparation of docetaxel, its intermediates, and methods for preparation thereof | SHANGHAI PARLING PHARMA-TECH. CO., LTD. (CN) | 2014-02-25 | — | — | US | disclosed |
| WO-2012088391-A1 | NON-RING HYDROXY SUBSTITUTED TAXANES AND METHODS FOR SYNTHESIZING THE SAME | NEKTAR THERAPEUTICS (US) | 2012-06-28 | — | — | WO | disclosed |
| US-20100228038-A1 | PROCESSES FOR THE PRODUCTION OF POLYCYCLIC FUSED RING COMPOUNDS | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2010-09-09 | — | — | US | disclosed |
| US-7667055-B2 | Processes for the production of polycyclic fused ring compounds | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2010-02-23 | — | — | US | disclosed |
| US-7550608-B2 | Processes for the preparation of docetaxel | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2009-06-23 | — | — | US | disclosed |
| US-7541458-B2 | β-lactam synthesis | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2009-06-02 | — | — | US | disclosed |
| US-7358378-B2 | Processes for the preparation of paclitaxel | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2008-04-15 | — | — | US | disclosed |
| EP-0681568-B1 | PROCESS FOR PREPARATION OF TAXANE DERIVATIVES AND BETA-LACTAM INTERMEDIATES THEREFOR | UNIV NEW YORK STATE RES FOUND (US) | 2006-07-26 | — | — | EP | disclosed |
| US-6218553-B1 | METALLIZATION BY REACTING A BACCATIN III DERIVATIVE WITH A METAL ALKYLDISILAZIDE | THE STATE UNIVERSITY OF NEW YORK AT STONY BROOK | 2001-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100228038-A1 | PROCESSES FOR THE PRODUCTION OF POLYCYCLIC FUSED RING COMPOUNDS | COASY, PARG, PIN4 | ELANE 4817/4885ABCB1 2404/4885KLK7 1470/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.