Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KLK7 | P49862 | 1/20 | 0.33 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5963965 | 1.00 | EPHX1 (0.34) | EPHX1HPGDKLK7KLK5ALDH1A1 | |
| SCHEMBL5963853 | 0.83 | BACE1 (0.31) | EPHX1HPGDKLK7KLK5ALDH1A1 | |
| SCHEMBL6601054 | 0.78 | HPGD (0.38) | EPHX1HPGDALDH1A1MAPTMEN1 | |
| SCHEMBL6601061 | 0.78 | HPGD (0.38) | EPHX1HPGDALDH1A1MAPTMEN1 | |
| SCHEMBL6601058 | 0.78 | HPGD (0.38) | EPHX1HPGDALDH1A1MAPTMEN1 | |
| SCHEMBL5963831 | 0.78 | KLK7 (0.33) | KLK7KLK5PLA2G10PLA2G5ELANE | |
| SCHEMBL6599274 | 0.77 | TPSAB1 (0.36) | EPHX1HPGDALDH1A1MAPTMEN1 | |
| SCHEMBL6599271 | 0.77 | TPSAB1 (0.36) | EPHX1HPGDALDH1A1MAPTMEN1 | |
| SCHEMBL6599280 | 0.77 | TPSAB1 (0.36) | EPHX1HPGDALDH1A1MAPTMEN1 | |
| SCHEMBL6600507 | 0.74 | TPSAB1 (0.36) | HPGDALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0681568-B1 | PROCESS FOR PREPARATION OF TAXANE DERIVATIVES AND BETA-LACTAM INTERMEDIATES THEREFOR | UNIV NEW YORK STATE RES FOUND (US) | 2006-07-26 | — | — | EP | disclosed |