SCHEMBL5964535

SCHEMBL5964535

CCCCOc1nc(N)c2[nH]c(=O)n(CCCNc3cccc(OC(C)=O)c3)c2n1

nearest known ligand 0.57

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 19/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27683217 0.89 TLR7 (0.59) TLR7
SCHEMBL2389401 0.86 TLR7 (0.64) TLR7
SCHEMBL17473815 0.86 TLR7 (0.54) TLR7
SCHEMBL17473811 0.86 TLR7 (0.68) TLR7
SCHEMBL5964658 0.86 TLR7 (0.70) TLR7
SCHEMBL12047494 0.86 TLR7 (0.75) TLR7
SCHEMBL2388529 0.84 TLR7 (0.65) TLR7
SCHEMBL5522471 0.84 TLR7 (0.56) TLR7
SCHEMBL17473799 0.83 TLR7 (0.53) TLR7
SCHEMBL17473806 0.82 TLR7 (0.48) TLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1728793-A1 9-SUBSTITUTED 8-OXOADENINE COMPOUND Dainippon Sumitomo Pharma Co., Ltd. (JP) 2006-12-06 EP disclosed