SCHEMBL5522471

SCHEMBL5522471

CCCCOc1nc(N)c2[nH]c(=O)n(CCSc3cccc(OC(C)=O)c3)c2n1

nearest known ligand 0.56

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 19/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2391723 0.89 TLR7 (0.54) TLR7
SCHEMBL2388778 0.86 TLR7 (0.63) TLR7
SCHEMBL12049013 0.85 TLR7 (0.76) TLR7
SCHEMBL5964658 0.84 TLR7 (0.70) TLR7
SCHEMBL5964535 0.84 TLR7 (0.57) TLR7
SCHEMBL5523819 0.84 TLR7 (0.55) TLR7
SCHEMBL2391717 0.84 TLR7 (0.54) TLR7
SCHEMBL2389638 0.84 TLR7 (0.66) TLR7
SCHEMBL17473811 0.83 TLR7 (0.68) TLR7
SCHEMBL17473815 0.81 TLR7 (0.54) TLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070190071-A1 9-Substituted 8-oxoadenine compound DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) 2007-08-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070190071-A1 9-Substituted 8-oxoadenine compound IFNAR1, IL5, IFNG TLR7 8/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.