Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 14/20 | 0.52 |
| ▸ | NPY1R | P25929 | 9/20 | 0.52 |
| ▸ | NPY5R | Q15761 | 9/20 | 0.52 |
| ▸ | NPY2R | P49146 | 6/20 | 0.52 |
| ▸ | CD40 | P25942 | 1/20 | 0.52 |
| ▸ | TFPI | P10646 | 1/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.51 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.49 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5965085 | 1.00 | NPY4R (0.52) | NPY4RNPY1RNPY5RNPY2RCD40 | |
| SCHEMBL30939697 | 1.00 | NPY4R (0.52) | NPY4RNPY1RNPY5RNPY2RCD40 | |
| SCHEMBL30939704 | 1.00 | NPY4R (0.52) | NPY4RNPY1RNPY5RNPY2RCD40 | |
| SCHEMBL31232432 | 1.00 | NPY4R (0.52) | NPY4RNPY1RNPY5RNPY2RCD40 | |
| SCHEMBL31078217 | 0.98 | NPY4R (0.52) | NPY4RNPY1RNPY5RNPY2RCD40 | |
| SCHEMBL30787045 | 0.96 | NPY4R (0.52) | NPY4RNPY1RNPY5RNPY2RCD40 | |
| SCHEMBL30787044 | 0.94 | NPY4R (0.57) | NPY4RNPY1RNPY5RNPY2RCD40 | |
| SCHEMBL30787054 | 0.94 | NPY4R (0.57) | NPY4RNPY1RNPY5RNPY2RCD40 | |
| SCHEMBL30787061 | 0.94 | NPY4R (0.57) | NPY4RNPY1RNPY5RNPY2RCD40 | |
| SCHEMBL29482485 | 0.94 | NPY4R (0.57) | NPY4RNPY1RNPY5RNPY2RCD40 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005117538-A9 | METHODS AND COMPOSITIONS FOR INHIBITING ABAD/Aβ PROTEIN INTERACTION | UNIV COLUMBIA (US) | 2006-12-07 | — | — | WO | disclosed |
| WO-2005117538-A2 | METHODS AND COMPOSITIONS FOR INHIBITING ABAD/Aβ PROTEIN INTERACTION | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2005-12-15 | — | — | WO | disclosed |