SCHEMBL5965085

SCHEMBL5965085

N=C(N)NCCC[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ NPY4R P50391 14/20 0.52
▸ NPY1R P25929 9/20 0.52
▸ NPY5R Q15761 9/20 0.52
▸ NPY2R P49146 6/20 0.52
▸ CD40 P25942 1/20 0.52
▸ TFPI P10646 1/20 0.51
▸ KEAP1 Q14145 1/20 0.51
▸ ERAP2 Q6P179 1/20 0.49
▸ LNPEP Q9UIQ6 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30939697 1.00 NPY4R (0.52) NPY4RNPY1RNPY5RNPY2RCD40
SCHEMBL30939704 1.00 NPY4R (0.52) NPY4RNPY1RNPY5RNPY2RCD40
SCHEMBL31232432 1.00 NPY4R (0.52) NPY4RNPY1RNPY5RNPY2RCD40
SCHEMBL5965061 1.00 NPY4R (0.52) NPY4RNPY1RNPY5RNPY2RCD40
SCHEMBL31078217 0.98 NPY4R (0.52) NPY4RNPY1RNPY5RNPY2RCD40
SCHEMBL30787045 0.96 NPY4R (0.52) NPY4RNPY1RNPY5RNPY2RCD40
SCHEMBL30787044 0.94 NPY4R (0.57) NPY4RNPY1RNPY5RNPY2RCD40
SCHEMBL30787054 0.94 NPY4R (0.57) NPY4RNPY1RNPY5RNPY2RCD40
SCHEMBL30787061 0.94 NPY4R (0.57) NPY4RNPY1RNPY5RNPY2RCD40
SCHEMBL29482485 0.94 NPY4R (0.57) NPY4RNPY1RNPY5RNPY2RCD40

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119823255-A Nur77 methylation site mutant peptide designed based on structural modification and application thereof in promoting embryo implantation 南京鼓楼医院 2025-04-15 — — CN disclosed
US-20250115640-A1 NEUROPROTECTIVE POLYPEPTIDE COMPOUND AND APPLICATION THEREOF INNERSE (ZHUHAI) PHARMACEUTICAL CO., LTD. (CN) 2025-04-10 — — US disclosed
CN-119462849-A Polypeptide and application thereof in neurodegenerative diseases 天津智泰生物医药科技有限公司 2025-02-18 — — CN disclosed
CN-113735938-B Neuroprotective polypeptide compound and application thereof 英纳氏(珠海)药业有限公司 2024-11-08 — — CN disclosed
US-20240368230-A1 CELL-PENETRATING PEPTIDES COMPRISING MULTIPLE 5-MER ALPHA-HELIX FRAGMENTS AND USES THEREOF ARTPROBIO CO., LTD. (KR) 2024-11-07 — — US disclosed
CN-118698507-A Preparation method of phospholipid affinity monolithic column and application of monolithic column 无锡萃纯生物材料科技有限公司 2024-09-27 — — CN disclosed
CN-118638745-A Method for purifying lentivirus 无锡萃纯生物材料科技有限公司 2024-09-13 — — CN disclosed
EP-4378949-A1 NEUROPROTECTIVE POLYPEPTIDE COMPOUND AND APPLICATION THEREOF Innerse (Zhuhai) Pharmaceutical Co., Ltd. (CN) 2024-06-05 — — EP disclosed
CN-117003829-A Oil control polypeptide compound, preparation method and application thereof 成都凯捷多肽科技有限公司 2023-11-07 — — CN disclosed
CN-115838434-A Polypeptide analogue and application thereof in medicine 南通大学 2023-03-24 — — CN disclosed
WO-2023006083-A1 NEUROPROTECTIVE POLYPEPTIDE COMPOUND AND APPLICATION THEREOF 英纳氏(珠海)药业有限公司 2023-02-02 — — WO disclosed
US-20220362381-A1 REMOTELY TRIGGERED THERAPY BAMBU VAULT LLC (US) 2022-11-17 — — US disclosed
WO-2005117538-A9 METHODS AND COMPOSITIONS FOR INHIBITING ABAD/Aβ PROTEIN INTERACTION UNIV COLUMBIA (US) 2006-12-07 — — WO disclosed
WO-2005117538-A2 METHODS AND COMPOSITIONS FOR INHIBITING ABAD/Aβ PROTEIN INTERACTION THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2005-12-15 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220362381-A1 REMOTELY TRIGGERED THERAPY CD47, HSP90AA1, HSF1 NPY4R 1871/4885NPY1R 2493/4885NPY5R 3059/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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