Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 15/20 | 0.76 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5309879 | 0.89 | PTGS2 (0.68) | PTGS2PTGS1 | |
| SCHEMBL7212067 | 0.89 | PTGS2 (0.76) | PTGS2PTGS1 | |
| SCHEMBL5308946 | 0.86 | PTGS2 (0.73) | PTGS2PTGS1 | |
| SCHEMBL5311535 | 0.86 | PTGS2 (0.73) | PTGS2PTGS1 | |
| SCHEMBL7210478 | 0.86 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL7212040 | 0.86 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL6517130 | 0.86 | PTGS2 (0.64) | PTGS2PTGS1 | |
| SCHEMBL5311830 | 0.84 | PTGS2 (0.73) | PTGS2PTGS1 | |
| SCHEMBL5308966 | 0.84 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL5313386 | 0.83 | PTGS2 (1.00) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE39420-E1 | 1,2-Diphenylpyrrole derivatives, their preparation and their therapeutic uses | SANKYO COMPANY, LIMITED (JP) | 2006-12-05 | — | — | US | disclosed |
| CN-1151126-C | 1, 2-diphenylpyrrole derivatives, their preparation and their therapeutic uses | ������������ʽ���� | 2004-05-26 | — | — | CN | disclosed |
| US-5908858-A | OSTEOPOROSIS; LEUKOTRIENE INHIBITOR | SANKYO COMPANY, LIMITED (JP) | 1999-06-01 | — | — | US | disclosed |
| CN-1168372-A | 1, 2-diphenylpyrrole derivatives, their preparation and their therapeutic uses | SANKYO CO (JP) | 1997-12-24 | — | — | CN | disclosed |
| EP-0799823-A1 | 1,2-Diphenylpyrrole derivatives, their preparation and their therapeutic uses | SANKYO COMPANY LIMITED (JP) | 1997-10-08 | — | — | EP | disclosed |