SCHEMBL5965482

SCHEMBL5965482

COC(=O)c1c(C(=O)c2ccccc2)cc(C(=O)O)c(C(=O)O)c1C(=O)OC

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 3/20 0.51
TSHR P16473 1/20 0.49
POLB P06746 1/20 0.45
KDM4E B2RXH2 2/20 0.45
CYP2C8 P10632 1/20 0.45
CYP2C9 P11712 1/20 0.45
HPGD P15428 3/20 0.44
HTT P42858 3/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
LMNA P02545 3/20 0.43
ALDH1A1 P00352 3/20 0.43
HSD17B10 Q99714 2/20 0.43
SLC6A3 Q01959 2/20 0.43
CYP1A2 P05177 1/20 0.43
PGR P06401 1/20 0.43
CYP2D6 P10635 1/20 0.43
SLC6A2 P23975 1/20 0.43
PDE4A P27815 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8674887 0.89 TSHR (0.53) AKR1C3TSHRPOLBKDM4ECYP2C8
SCHEMBL8640547 0.84 AKR1C3 (0.47) AKR1C3TSHRPOLBKDM4ECYP2C8
SCHEMBL76089 0.84 AKR1C3 (0.67) AKR1C3POLBKDM4ECYP2C8CYP2C9
SCHEMBL8660209 0.83 ALDH1A1 (0.58) AKR1C3POLBCYP2C9HPGDHTT
SCHEMBL6890474 0.82 AKR1C3 (0.64) AKR1C3POLBKDM4ECYP2C8CYP2C9
Hydrochloric Acid SCHEMBL10800610 0.82 AKR1C3 (0.64) AKR1C3POLBKDM4ECYP2C8CYP2C9
Pyromellitic Acid SCHEMBL1639949 0.82 AKR1C3 (0.64) AKR1C3POLBKDM4ECYP2C8CYP2C9
Water SCHEMBL7457263 0.82 AKR1C3 (0.64) AKR1C3POLBKDM4ECYP2C8CYP2C9
Hydrochloric Acid SCHEMBL28386965 0.82 AKR1C3 (0.64) AKR1C3POLBKDM4ECYP2C8CYP2C9
Ammonia Solution, Strong SCHEMBL11271162 0.82 AKR1C3 (0.64) AKR1C3POLBKDM4ECYP2C8CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4877563-A MICROWAVE RADIATION TREATMENT OF POLYIMIDE FOAM USING SHIELD TO CURTAIL FOAMING ON BOTTOM SURFACE ETHYL CORPORATION (US) 1989-10-31 US claimed
US-9824797-B2 Resistive grid elements having a thermosetting polymer GENERAL ELECTRIC COMPANY (US) 2017-11-21 US disclosed
US-20160180990-A1 RESISTIVE GRID ELEMENTS HAVING A THERMOSETTING POLYMER GE GLOBAL SOURCING LLC 2016-06-23 US disclosed
EP-1051440-B1 LOW-TOXICITY, HIGH-TEMPERATURE POLYIMIDES MAVERICK CORP (US) 2006-08-30 EP disclosed
EP-0776924-B1 Polyimide composition and method for producing prepreg and paint using the same MITSUBISHI HEAVY IND LTD (JP) 2003-09-24 EP disclosed
US-6184333-B1 Thermal oxidation stability; high glass transition temperature; monomer mixture includes alpha,alpha'-bis(p-aminophenyl)-(m or p)-diisopropylbenzene, and does not include more than one type of aromatic dianhydride, a diaminosiloxane, or a diaryl substituted acetylene end-capping agent MAVERICK CORPORATION 2001-02-06 US disclosed
EP-1051440-A1 LOW-TOXICITY, HIGH-TEMPERATURE POLYIMIDES Maverick Corporation (US) 2000-11-15 EP disclosed
US-6036900-A Resin transfer imidization of polyimide matrix composites GENERAL ELECTRIC COMPANY (US) 2000-03-14 US disclosed
WO-1999036462-A1 LOW-TOXICITY, HIGH-TEMPERATURE POLYIMIDES MAVERICK CORPORATION (US) 1999-07-22 WO disclosed
US-5914385-A Polyimide resin composition and method for producing prepreg and paint and method for curing resin using the same MITSUBISHI JUKOGYO KABUSHIKI KAISHA (JP) 1999-06-22 US disclosed
EP-0348722-A1 Production of foamed polymer structures Imi-Tech Corporation (US) 1990-01-03 EP disclosed
US-4877563-A MICROWAVE RADIATION TREATMENT OF POLYIMIDE FOAM USING SHIELD TO CURTAIL FOAMING ON BOTTOM SURFACE ETHYL CORPORATION (US) 1989-10-31 US disclosed
US-4866104-A FLEXIBILITY, SOFTNESS ETHYL CORPORATION (US) 1989-09-12 US disclosed
US-4855331-A FOAMING BY MICROWAVE RADIATION UNDER A VAPOR IMPERMIABLE SHIEL D ETHYL CORPORATION (US) 1989-08-08 US disclosed
US-4855332-A 2-/VICINAL-DICARBOXYCYCLOHEXENYUL/SUCCINIC ACID ETHYL CORPORATION (US) 1989-08-08 US disclosed
US-4826886-A AIRCRAFT SEAT CUSHIONS ETHYL CORPORATION (US) 1989-05-02 US disclosed
US-4822537-A MICROWAVE IRRADIATION OF POLYIMIDE ETHYL CORPORATION (US) 1989-04-18 US disclosed
US-4804504-A MICROWAVE RADIATION OF POLYIMIDE PRECURSOR UNDER VAPOR IMPERMEABLE COVERING ETHYL CORPORATION (US) 1989-02-14 US disclosed
US-4533737-A Silicon functionalized norbornane carboxyimide and methods for making GENERAL ELECTRIC COMPANY (US) 1985-08-06 US disclosed
US-4517342-A Heat curable compositions GENERAL ELECTRIC COMPANY (US) 1985-05-14 US disclosed