Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11628782 | 0.83 | MCL1 (0.39) | MCL1 | |
| SCHEMBL28880756 | 0.77 | MCL1 (0.36) | MCL1 | |
| SCHEMBL11842620 | 0.76 | ALOX15 (0.41) | MCL1 | |
| SCHEMBL28289211 | 0.76 | TSHR (0.36) | — | |
| SCHEMBL319578 | 0.75 | — | — | |
| SCHEMBL28250881 | 0.75 | — | — | |
| SCHEMBL28773374 | 0.75 | — | — | |
| SCHEMBL10500307 | 0.75 | MCL1 (0.36) | MCL1 | |
| SCHEMBL7431413 | 0.74 | — | — | |
| SCHEMBL3917719 | 0.73 | SLC7A5 (0.39) | MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060094682-A1 | Kinase inhibitors for the treatment of diabetes and obesity | ODYSSEY THERA, INC. (US) | 2006-05-04 | — | — | US | disclosed |
| EP-0645379-B1 | Benzoylacetylene derivatives | MITSUBISHI CHEM CORP (JP) | 1999-03-17 | — | — | EP | disclosed |
| US-5618829-A | SUPPRESSION GROWTH OF CANCER CELLS | MITSUBISHI CHEMICAL CORPORATION (JP) | 1997-04-08 | — | — | US | disclosed |
| EP-0645379-A2 | Benzoylacetylene derivatives | Mitsubishi Chemical Corporation (JP) | 1995-03-29 | — | — | EP | disclosed |
| EP-0608897-A2 | Tyrosine kinase inhibitors and benzoylacrylamide derivatives | Mitsubishi Chemical Corporation (JP) | 1994-08-03 | — | — | EP | disclosed |