SCHEMBL5969669

SCHEMBL5969669

CCOC(=O)C(C)(C)Oc1ccc(-c2nc(-c3ccc(OC(C)(C)C(=O)OCC)cc3O)nc(-c3ccc(OC(C)(C)C(=O)OCC)cc3O)n2)c(O)c1

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ PPARA Q07869 5/20 0.56
▸ ABCB11 O95342 1/20 0.56
▸ CYP1A2 P05177 1/20 0.56
▸ CYP3A4 P08684 1/20 0.56
▸ TSHR P16473 1/20 0.56
▸ HTR2A P28223 1/20 0.56
▸ PMP22 Q01453 1/20 0.56
▸ PPARG P37231 4/20 0.48
▸ FBP1 P09467 9/20 0.46
▸ NPC1 O15118 1/20 0.40
▸ KDM4E B2RXH2 1/20 0.38
▸ GAA P10253 1/20 0.38
▸ MAPT P10636 1/20 0.38
▸ GRM2 Q14416 1/20 0.38
▸ F2 P00734 1/20 0.38
▸ F10 P00742 1/20 0.38
▸ PLG P00747 1/20 0.38
▸ PRSS1 P07477 1/20 0.38
▸ OPRK1 P41145 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15721394 0.92 PPARA (0.48) PPARAABCB11CYP1A2CYP3A4TSHR
SCHEMBL8382360 0.92 PPARA (0.48) PPARAABCB11CYP1A2CYP3A4TSHR
SCHEMBL7137069 0.88 PPARA (0.46) PPARAABCB11CYP1A2CYP3A4TSHR
SCHEMBL27497081 0.87 PPARA (0.51) PPARAABCB11CYP1A2CYP3A4TSHR
SCHEMBL7131940 0.87 PPARA (0.48) PPARAABCB11CYP1A2CYP3A4TSHR
SCHEMBL7133479 0.86 PPARA (0.50) PPARAABCB11CYP1A2CYP3A4TSHR
SCHEMBL7139298 0.86 PPARA (0.50) PPARAABCB11CYP1A2CYP3A4TSHR
SCHEMBL13431066 0.85 PPARA (0.48) PPARAABCB11CYP1A2CYP3A4TSHR
SCHEMBL7141799 0.85 NPC1 (0.47) PPARAABCB11CYP1A2CYP3A4TSHR
SCHEMBL6035075 0.83 PPARA (0.61) PPARAABCB11CYP1A2CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6509400-B2 2,4,6-Tris(2-hydroxyphenyl)-s-triazines as stabilizers for organic polymers used for coatings for wood and automobiles; radiation, oxidation and heat resistance; protective coatings; weatherproofing; alkyd resins CIBA SPECIALTY CHEMICALS CORPORATION 2003-01-21 — — US claimed
US-20020086922-A1 Trisresorcinyltriazines SCHAFER THOMAS (CH) 2002-07-04 — — US claimed
US-6346619-B1 POLYESTERS WITH WEATHERPROOFING, OXIDATION RESISTANCE FOR OPTICAL ISOMERS CIBA SPECIALTY CHEMICALS CORPORATION 2002-02-12 — — US claimed
EP-1242391-B1 STABILIZER MIXTURE CIBA SC HOLDING AG (CH) 2006-02-22 — — EP disclosed
US-6913712-B2 Stabilizer mixture CIBA SPECIALTY CHEMICALS CORP. (US) 2005-07-05 — — US disclosed
US-20030096993-A1 Stabilizer mixture CIBA SPECIALTY CHEMICALS CORP. 2003-05-22 — — US disclosed
US-6509400-B2 2,4,6-Tris(2-hydroxyphenyl)-s-triazines as stabilizers for organic polymers used for coatings for wood and automobiles; radiation, oxidation and heat resistance; protective coatings; weatherproofing; alkyd resins CIBA SPECIALTY CHEMICALS CORPORATION 2003-01-21 — — US disclosed
EP-1242391-A1 STABILIZER MIXTURE Ciba SC Holding AG (CH) 2002-09-25 — — EP disclosed
US-20020086922-A1 Trisresorcinyltriazines SCHAFER THOMAS (CH) 2002-07-04 — — US disclosed
US-6346619-B1 POLYESTERS WITH WEATHERPROOFING, OXIDATION RESISTANCE FOR OPTICAL ISOMERS CIBA SPECIALTY CHEMICALS CORPORATION 2002-02-12 — — US disclosed
WO-2001047900-A1 STABILIZER MIXTURE CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2001-07-05 — — WO disclosed
US-6117997-A STABILIZERS AGAINST HEAT, OXIDATION, RADIATION CIBA SPECIALTY CHEMICALS CORPORATION (US) 2000-09-12 — — US disclosed
JP-2000026435-A TRISRESORCINYLTRIAZINE CIBA SPECIALTY CHEM HOLDING INC 2000-01-25 — — JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020086922-A1 Trisresorcinyltriazines CBR1, CBR3, CYCS PPARA 3538/4885ABCB11 674/4885CYP1A2 153/4885
US-20030096993-A1 Stabilizer mixture GSR, GLRA1, GLRA2 PPARA 2869/4885ABCB11 2057/4885CYP1A2 1648/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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