Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CCR5 | P51681 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | PTGIR | P43119 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5969612 | 0.92 | CHRM1 (0.45) | MEN1KMT2ACCR5OPRM1CHRM1 | |
| SCHEMBL5969497 | 0.90 | MEN1 (0.47) | MEN1KMT2ACCR5OPRM1CHRM1 | |
| SCHEMBL5969498 | 0.89 | CHRM1 (0.43) | MEN1KMT2ACCR5CHRM1CHRM3 | |
| SCHEMBL5969556 | 0.89 | MEN1 (0.47) | MEN1KMT2ACCR5OPRM1CHRM3 | |
| SCHEMBL5969489 | 0.89 | HRH3 (0.43) | MEN1KMT2ACCR5CHRM1CHRM3 | |
| SCHEMBL5969529 | 0.88 | MEN1 (0.48) | MEN1KMT2ACCR5OPRM1CHRM1 | |
| SCHEMBL5969549 | 0.87 | MEN1 (0.45) | MEN1KMT2ACCR5OPRM1CHRM1 | |
| SCHEMBL5969511 | 0.87 | CETP (0.45) | MEN1KMT2ACCR5OPRM1PTGIR | |
| SCHEMBL4312474 | 0.86 | MEN1 (0.44) | MEN1KMT2ACCR5OPRM1ACHE | |
| SCHEMBL4315157 | 0.86 | MEN1 (0.49) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1556045-B1 | 4-AMINOPIPERIDINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | UCB SA (BE) | 2006-08-02 | — | — | EP | claimed |