Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | DCUN1D1 | Q96GG9 | 4/20 | 0.42 |
| ▸ | UBE2M | P61081 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CCR5 | P51681 | 3/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.40 |
| ▸ | HPGDS | O60760 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CETP | P11597 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5969497 | 0.91 | MEN1 (0.47) | MEN1KMT2AKCNH2DCUN1D1UBE2M | |
| SCHEMBL5969537 | 0.90 | CCR5 (0.49) | KCNH2DCUN1D1UBE2MCYP3A4CCR5 | |
| SCHEMBL5969908 | 0.88 | CCR5 (0.43) | KCNH2DCUN1D1UBE2MCYP3A4CCR5 | |
| SCHEMBL5969511 | 0.88 | CETP (0.45) | MEN1KMT2AKCNH2DCUN1D1UBE2M | |
| SCHEMBL5969556 | 0.88 | MEN1 (0.47) | MEN1KMT2AKCNH2CCR5ACHE | |
| SCHEMBL5969415 | 0.88 | CYP3A4 (0.46) | MEN1KMT2AKCNH2DCUN1D1UBE2M | |
| SCHEMBL4307525 | 0.88 | CYP3A4 (0.46) | MEN1KMT2AKCNH2DCUN1D1UBE2M | |
| SCHEMBL4302437 | 0.87 | TGFBR1 (0.50) | MEN1KMT2A | |
| SCHEMBL5969945 | 0.86 | MEN1 (0.44) | MEN1KMT2ACCR5ACHEOPRM1 | |
| SCHEMBL5969599 | 0.84 | TACR1 (0.42) | MEN1KMT2AKCNH2DCUN1D1UBE2M |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7488741-B2 | 4-Aminopiperidine derivatives, processes for their preparation and their use as medicaments | UCB PHARMA, S.A. (BE) | 2009-02-10 | — | — | US | claimed |
| EP-1556045-B1 | 4-AMINOPIPERIDINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | UCB SA (BE) | 2006-08-02 | — | — | EP | claimed |