Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.80 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.80 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.80 |
| ▸ | RAF1 | P04049 | 1/20 | 0.80 |
| ▸ | CDK1 | P06493 | 1/20 | 0.80 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.80 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.57 |
| ▸ | TUBB | P07437 | 2/20 | 0.57 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.57 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.57 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.57 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.57 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.57 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.57 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.57 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.57 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.57 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.57 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL79639 | 1.00 | CYP1A2 (0.80) | CYP1A2CYP2C9CYP2C19RAF1CDK1 | |
| SCHEMBL5972022 | 1.00 | CYP1A2 (0.80) | CYP1A2CYP2C9CYP2C19RAF1CDK1 | |
| SCHEMBL79872 | 1.00 | CYP1A2 (0.80) | CYP1A2CYP2C9CYP2C19RAF1CDK1 | |
| Plinabulin SCHEMBL28720406 | 0.89 | CYP1A2 (1.00) | CYP1A2CYP2C9CYP2C19RAF1CDK1 | |
| Plinabulin SCHEMBL21050030 | 0.89 | CYP1A2 (1.00) | CYP1A2CYP2C9CYP2C19RAF1CDK1 | |
| Plinabulin SCHEMBL79095 | 0.89 | CYP1A2 (1.00) | CYP1A2CYP2C9CYP2C19RAF1CDK1 | |
| Plinabulin SCHEMBL29216847 | 0.89 | CYP1A2 (1.00) | CYP1A2CYP2C9CYP2C19RAF1CDK1 | |
| Plinabulin SCHEMBL17979608 | 0.89 | CYP1A2 (1.00) | CYP1A2CYP2C9CYP2C19RAF1CDK1 | |
| Plinabulin SCHEMBL29033820 | 0.89 | CYP1A2 (1.00) | CYP1A2CYP2C9CYP2C19RAF1CDK1 | |
| Plinabulin SCHEMBL31329443 | 0.88 | CYP1A2 (0.97) | CYP1A2CYP2C9CYP2C19RAF1CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060079534-A1 | Cell division inhibitor and a production method thereof | BEYONDSPRING PHARMACEUTICALS, INC. | 2006-04-13 | — | — | US | claimed |
| US-6972289-B1 | Cell division inhibitor and a production method thereof | NEREUS PHARMACEUTICALS, INC. (US) | 2005-12-06 | — | — | US | disclosed |
| EP-1264831-A1 | CELL DIVISION INHIBITORS AND PROCESS FOR PRODUCING THE SAME | Nereus Pharmaceuticals, Inc. (US) | 2002-12-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060079534-A1 | Cell division inhibitor and a production method thereof | DHPS, CDC16, CDC45 | CYP1A2 1492/4885CYP2C9 2945/4885CYP2C19 1849/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.