Asulam

Asulam

SCHEMBL5973006

COC(=O)NS(=O)(=O)c1ccc(N)cc1.[CaH2]

nearest known ligand 0.66

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.66
DHFR P00374 1/20 0.66
TSHR P16473 1/20 0.66
TDP1 Q9NUW8 1/20 0.66
ALDH1A1 P00352 2/20 0.60
LMNA P02545 3/20 0.54
MEN1 O00255 2/20 0.54
KMT2A Q03164 2/20 0.54
CA1 P00915 3/20 0.53
CA2 P00918 3/20 0.53
MMP1 P03956 2/20 0.53
MMP2 P08253 2/20 0.53
MMP9 P14780 2/20 0.53
MMP13 P45452 2/20 0.53
MMP8 P22894 1/20 0.53
FBP1 P09467 1/20 0.50
F2 P00734 2/20 0.47
PRSS1 P07477 2/20 0.47
PRSS2 P07478 2/20 0.47
PRSS3 P35030 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Asulam SCHEMBL64856 0.98 SMN1; SMN2 (0.68) SMN1; SMN2DHFRTSHRTDP1ALDH1A1
Asulam SCHEMBL16899633 0.98 SMN1; SMN2 (0.68) SMN1; SMN2DHFRTSHRTDP1ALDH1A1
Asulam SCHEMBL5933799 0.96 SMN1; SMN2 (0.66) SMN1; SMN2DHFRTSHRTDP1ALDH1A1
Asulam SCHEMBL30124311 0.96 SMN1; SMN2 (0.66) SMN1; SMN2DHFRTSHRTDP1ALDH1A1
Asulam SCHEMBL30719581 0.96 SMN1; SMN2 (0.66) SMN1; SMN2DHFRTSHRTDP1ALDH1A1
Asulam SCHEMBL2146039 0.96 SMN1; SMN2 (0.66) SMN1; SMN2DHFRTSHRTDP1ALDH1A1
Asulam SCHEMBL4659880 0.93 SMN1; SMN2 (0.62) SMN1; SMN2DHFRTSHRTDP1ALDH1A1
Asulam SCHEMBL96347 0.92 TSHR (0.60) SMN1; SMN2DHFRTSHRTDP1ALDH1A1
Asulam SCHEMBL9371267 0.90 SMN1; SMN2 (0.58) SMN1; SMN2DHFRTSHRTDP1ALDH1A1
Asulam SCHEMBL9738696 0.84 SMN1; SMN2 (0.51) SMN1; SMN2DHFRTSHRTDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1618784-A1 AQUEOUS AGRICULTURAL-CHEMICAL SUSPENSION COMPOSITION KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2006-01-25 EP disclosed