Asulam

Asulam

SCHEMBL96347

COC(=O)NS(=O)(=O)c1ccc(N)cc1.Nc1ccc(S(N)(=O)=O)cc1

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

folP

The experimentally established mechanism targets of Asulam. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.60
TDP1 Q9NUW8 2/20 0.60
DHFR P00374 1/20 0.60
SMN1; SMN2 Q16637 1/20 0.60
ALDH1A1 P00352 2/20 0.55
CA2 P00918 14/20 0.55
CA1 P00915 13/20 0.55
CA9 Q16790 13/20 0.55
CA12 O43570 11/20 0.55
CA14 Q9ULX7 7/20 0.55
CA7 P43166 5/20 0.55
CA6 P23280 4/20 0.55
CA5A P35218 4/20 0.55
CA4 P22748 3/20 0.55
CA5B Q9Y2D0 3/20 0.55
CA13 Q8N1Q1 2/20 0.55
USP2 O75604 1/20 0.55
AGO2 Q9UKV8 1/20 0.55
HTT P42858 1/20 0.54
MEN1 O00255 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Asulam SCHEMBL64856 0.93 SMN1; SMN2 (0.68) TSHRTDP1DHFRSMN1; SMN2ALDH1A1
Asulam SCHEMBL16899633 0.93 SMN1; SMN2 (0.68) TSHRTDP1DHFRSMN1; SMN2ALDH1A1
Asulam SCHEMBL2146039 0.92 SMN1; SMN2 (0.66) TSHRTDP1DHFRSMN1; SMN2ALDH1A1
Asulam SCHEMBL30719581 0.92 SMN1; SMN2 (0.66) TSHRTDP1DHFRSMN1; SMN2ALDH1A1
Asulam SCHEMBL5933799 0.92 SMN1; SMN2 (0.66) TSHRTDP1DHFRSMN1; SMN2ALDH1A1
Asulam SCHEMBL30124311 0.92 SMN1; SMN2 (0.66) TSHRTDP1DHFRSMN1; SMN2ALDH1A1
Asulam SCHEMBL5973006 0.92 SMN1; SMN2 (0.66) TSHRTDP1DHFRSMN1; SMN2ALDH1A1
Asulam SCHEMBL9371267 0.89 SMN1; SMN2 (0.58) TSHRTDP1DHFRSMN1; SMN2ALDH1A1
Asulam SCHEMBL4659880 0.89 SMN1; SMN2 (0.62) TSHRTDP1DHFRSMN1; SMN2ALDH1A1
Sulfacetamide SCHEMBL1080661 0.83 TSHR (0.86) TSHRTDP1DHFRSMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150210742-A1 NOVEL ALLERGEN FROM RAGWEED POLLEN AND USES THEREOF STALLERGENES SA (FR) 2015-07-30 US disclosed
EP-2880049-A1 NOVEL ALLERGEN FROM RAGWEED POLLEN AND USES THEREOF Stallergenes S.A. (FR) 2015-06-10 EP disclosed
WO-2014020179-A1 NOVEL ALLERGEN FROM RAGWEED POLLEN AND USES THEREOF STALLERGENES S.A. (FR) 2014-02-06 WO disclosed
EP-2692732-A1 Novel allergen from ragweed pollen and uses thereof Stallergenes S.A. (FR) 2014-02-05 EP disclosed
US-20130326726-A1 Method for Inducing Mutations and/or Epimutations in Plants INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (FR) 2013-12-05 US disclosed
EP-2622083-A1 METHOD FOR INDUCING MUTATIONS AND/OR EPIMUTATIONS IN PLANTS Institut National De La Recherche Agronomique (FR) 2013-08-07 EP disclosed
US-8304603-B2 Plants with increased tolerance to water deficit Genoplante-Velor (FR) 2012-11-06 US disclosed
EP-2029753-B1 METHODS FOR OBTAINING PLANTS WITH INCREASED TOLERANCE TO WATER DEFICIT GENOPLANTE VALOR (FR) 2012-07-25 EP disclosed
WO-2012042486-A1 METHOD FOR INDUCING MUTATIONS AND/OR EPIMUTATIONS IN PLANTS INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (FR) 2012-04-05 WO disclosed
EP-2426207-A2 Plants with increased tolerance to water deficit Genoplante-Valor (FR) 2012-03-07 EP disclosed
US-20040139505-A1 Method for obtaining plants exhibiting enhanced resistance to water stress INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (FR) 2004-07-15 US disclosed
US-20040103457-A1 Overexpression of phosphoenolpyruvate carboxylase CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2004-05-27 US disclosed
EP-1395667-A2 METHOD FOR OBTAINING A MONOCOTYLEDON PLANT CONTAINING A GENE OF INTEREST FREE OF FOREIGN ANCILLARY SEQUENCE Rhobio (FR) 2004-03-10 EP disclosed
EP-1383902-A2 OVEREXPRESSION OF PHOSPHOENOLPYRUVATE CARBOXYLASE Biogemma (FR) 2004-01-28 EP disclosed
EP-1294900-A1 NUCLEIC ACIDS CODING FOR A PLANT PHOSPHATASE OF THE MIPP TYPE WITH PHYTASE ACTIVITY AND USES Biogemma (FR) 2003-03-26 EP disclosed
EP-1276870-A1 METHOD FOR OBTAINING PLANTS EXHIBITING ENHANCED RESISTANCE TO WATER STRESS Biogemma (FR) 2003-01-22 EP disclosed
WO-2002101061-A2 METHOD FOR OBTAINING A MONOCOTYLEDON PLANT CONTAINING A GENE OF INTEREST FREE OF FOREIGN ANCILLARY SEQUENCE RHOBIO (FR) 2002-12-19 WO disclosed
WO-2002081714-A2 OVEREXPRESSION OF PHOSPHOENOLPYRUVATE CARBOXYLASE BIOGEMMA (FR) 2002-10-17 WO disclosed
WO-2002000890-A1 NUCLEIC ACIDS CODING FOR A PLANT PHOSPHATASE OF THE MIPP TYPE WITH PHYTASE ACTIVITY AND USES BIOGEMMA (FR) 2002-01-03 WO disclosed
WO-2001083756-A1 METHOD FOR OBTAINING PLANTS EXHIBITING ENHANCED RESISTANCE TO WATER STRESS BIOGEMMA (FR) 2001-11-08 WO disclosed