Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN7 | P35236 | 5/20 | 0.70 |
| ▸ | HMGCR | P04035 | 3/20 | 0.70 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.59 |
| ▸ | FAAH | O00519 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22540052 | 1.00 | PTPN7 (0.70) | PTPN7HMGCRMEN1KMT2ASOAT1 | |
| SCHEMBL4225757 | 0.92 | HMGCR (0.72) | PTPN7HMGCRMEN1KMT2ASOAT1 | |
| SCHEMBL4231623 | 0.92 | HMGCR (0.72) | PTPN7HMGCRMEN1KMT2ASOAT1 | |
| SCHEMBL2182049 | 0.92 | HMGCR (0.72) | PTPN7HMGCRMEN1KMT2ASOAT1 | |
| SCHEMBL2180780 | 0.92 | HMGCR (0.72) | PTPN7HMGCRMEN1KMT2ASOAT1 | |
| SCHEMBL1918073 | 0.92 | HMGCR (0.72) | PTPN7HMGCRMEN1KMT2ASOAT1 | |
| SCHEMBL2201502 | 0.92 | HMGCR (0.72) | PTPN7HMGCRMEN1KMT2ASOAT1 | |
| SCHEMBL2181335 | 0.92 | HMGCR (0.72) | PTPN7HMGCRMEN1KMT2ASOAT1 | |
| SCHEMBL10963246 | 0.90 | RECQL (0.73) | PTPN7HMGCRMEN1KMT2ASOAT1 | |
| SCHEMBL10919003 | 0.90 | RECQL (0.73) | PTPN7HMGCRMEN1KMT2ASOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220112130-A1 | MAINTENANCE TREATMENTS USEFUL FOR IMPROVING THE PERFORMANCE OF AGED OR BRITTLE RESINOUS BINDERS IN PAVING OR ROOFING | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. | 2022-04-14 | — | — | US | disclosed |
| EP-1039902-B1 | INHIBITORS OF GAP JUNCTION COMMUNICATION | SCRIPPS RESEARCH INST (US) | 2006-03-08 | — | — | EP | disclosed |
| US-6858649-B1 | Selective potentiation of serotonin receptor subtypes | THE SCRIPPS RESEARCH INSTITUTE (US) | 2005-02-22 | — | — | US | disclosed |
| US-6734204-B1 | PERMIT SELECTIVE MODULATION OF OR EVEN HAVE OPPOSING EFFECTS ON DIFFERENT SEROTONIN RECEPTOR SUBTYPES | THE SCRIPPS RESEARCH INSTITUTE | 2004-05-11 | — | — | US | disclosed |
| EP-1073334-A4 | SEROTONIN POTENTIATION BY OLEAMIDE ANALOGS | SCRIPPS RESEARCH INST (US) | 2004-04-14 | — | — | EP | disclosed |
| EP-1039902-A4 | INHIBITORS OF GAP JUNCTION COMMUNICATION | SCRIPPS RESEARCH INST (US) | 2002-07-17 | — | — | EP | disclosed |
| US-6251931-B1 | OLEAMIDE AGONISTS AND AS INHIBITOR OF FATTY ACID AMIDE HYDROLASE FOR INHIBITION OF GAP JUNCTION-MEDIATED CHEMICAL AND ELECTRICAL TRANSMISSION IN GLIAL CELLS OF THE ANIMAL | THE SCRIPPS RESEARCH INSTITUTE | 2001-06-26 | — | — | US | disclosed |
| EP-1073334-A1 | SEROTONIN POTENTIATION BY OLEAMIDE ANALOGS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2001-02-07 | — | — | EP | disclosed |
| EP-1039902-A2 | INHIBITORS OF GAP JUNCTION COMMUNICATION | The Scripps Research Institute (US) | 2000-10-04 | — | — | EP | disclosed |
| WO-1999055159-A1 | SEROTONIN POTENTIATION BY OLEAMIDE ANALOGS | THE SCRIPPS RESEARCH INSTITUTE (US) | 1999-11-04 | — | — | WO | disclosed |
| WO-1999026584-A2 | INHIBITORS OF GAP JUNCTION COMMUNICATION | THE SCRIPPS RESEARCH INSTITUTE (US) | 1999-06-03 | — | — | WO | disclosed |