Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 2/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.73 |
| ▸ | PTPN7 | P35236 | 5/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.70 |
| ▸ | MEN1 | O00255 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | USP2 | O75604 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.70 |
| ▸ | POLB | P06746 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 1/20 | 0.70 |
| ▸ | HPGD | P15428 | 1/20 | 0.70 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.70 |
| ▸ | BLM | P54132 | 1/20 | 0.70 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.70 |
| ▸ | HMGCR | P04035 | 3/20 | 0.58 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.49 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10963246 | 1.00 | RECQL (0.73) | RECQLTDP1PTPN7KDM4EMEN1 | |
| SCHEMBL10803234 | 1.00 | RECQL (0.73) | RECQLTDP1PTPN7KDM4EMEN1 | |
| SCHEMBL10465224 | 0.98 | PTPN7 (0.72) | RECQLTDP1PTPN7KDM4EMEN1 | |
| SCHEMBL22540052 | 0.90 | PTPN7 (0.70) | RECQLTDP1PTPN7KDM4EMEN1 | |
| SCHEMBL5974171 | 0.90 | PTPN7 (0.70) | RECQLTDP1PTPN7KDM4EMEN1 | |
| SCHEMBL4453291 | 0.86 | PTPN7 (0.72) | RECQLTDP1PTPN7KDM4EMEN1 | |
| SCHEMBL3796753 | 0.86 | PTPN7 (0.72) | RECQLTDP1PTPN7KDM4EMEN1 | |
| SCHEMBL11071577 | 0.85 | TDP1 (1.00) | RECQLTDP1PTPN7KDM4EMEN1 | |
| SCHEMBL68425 | 0.85 | TDP1 (1.00) | RECQLTDP1PTPN7KDM4EMEN1 | |
| SCHEMBL10458369 | 0.85 | TDP1 (1.00) | RECQLTDP1PTPN7KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0104468-B1 | ARACHIDONIC ACID ANALOGUES AS ANTI-INFLAMMATORY AND ANTIALLERGIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1986-07-23 | — | — | EP | disclosed |
| EP-0104468-A1 | Arachidonic acid analogues as anti-inflammatory and antiallergic agents | SYNTEX (U.S.A.) INC. (US) | 1984-04-04 | — | — | EP | disclosed |