SCHEMBL597516

SCHEMBL597516

CC=Cc1ccc(N)cc1

nearest known ligand 0.59

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
APP P05067 2/20 0.59
CYP19A1 P11511 12/20 0.56
MAOA P21397 1/20 0.56
MAOB P27338 1/20 0.56
LMNA P02545 1/20 0.52
TP53 P04637 1/20 0.52
CYP3A4 P08684 1/20 0.52
TSHR P16473 1/20 0.52
KDM4E B2RXH2 1/20 0.52
ALDH1A1 P00352 1/20 0.52
NQO2 P16083 2/20 0.48
MEN1 O00255 1/20 0.44
MAPT P10636 1/20 0.44
KMT2A Q03164 1/20 0.44
CNR2 P34972 1/20 0.43
TYR P14679 1/20 0.42
ACHE P22303 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL597515 1.00 APP (0.59) APPCYP19A1MAOAMAOBLMNA
SCHEMBL1771676 1.00 APP (0.59) APPCYP19A1MAOAMAOBLMNA
Hydrochloric Acid SCHEMBL27543709 0.95 APP (0.54) APPCYP19A1MAOAMAOBLMNA
SCHEMBL24247893 0.93 CYP3A4 (0.52) APPCYP19A1MAOAMAOBLMNA
SCHEMBL9461723 0.85 CYP3A4 (0.65) APPLMNATP53CYP3A4TSHR
SCHEMBL333123 0.85 CYP3A4 (0.65) APPLMNATP53CYP3A4TSHR
SCHEMBL7527708 0.85 CYP3A4 (0.65) APPLMNATP53CYP3A4TSHR
SCHEMBL25673705 0.82 APP (0.73) APPCYP19A1MAOAMAOBNQO2
SCHEMBL9680836 0.82 CYP19A1 (0.78) APPCYP19A1MAOAMAOBTP53
SCHEMBL10459178 0.82 CYP19A1 (0.78) APPCYP19A1MAOAMAOBTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116688219-A Composite hemostatic material and preparation method thereof 浙江珂瑞康生物医疗科技有限公司 2023-09-05 CN claimed
CN-115998963-B Anticoagulation coating and preparation method and application thereof 上海发微医用材料有限公司 2023-07-21 CN claimed
CN-115998963-A Anticoagulation coating and preparation method and application thereof 上海发微医用材料有限公司 2023-04-25 CN claimed
CN-117142928-B Method for performing Diels-Alder reaction on photocatalytic dienophile and dienophile 陕西师范大学 2025-06-24 CN disclosed
CN-117142928-A Method for performing Diels-Alder reaction on photocatalytic dienophile and dienophile 陕西师范大学 2023-12-01 CN disclosed
CN-116688219-A Composite hemostatic material and preparation method thereof 浙江珂瑞康生物医疗科技有限公司 2023-09-05 CN disclosed
CN-115998963-B Anticoagulation coating and preparation method and application thereof 上海发微医用材料有限公司 2023-07-21 CN disclosed
CN-115998963-A Anticoagulation coating and preparation method and application thereof 上海发微医用材料有限公司 2023-04-25 CN disclosed
WO-2021212010-A2 SMALL MOLECULE ANTIVIRAL DRUG TREATMENT FOR HUMAN PAPILLOMAVIRUS INFECTIONS THE TRUSTEES OF INDIANA UNIVERSITY (US) 2021-10-21 WO disclosed
CN-105017162-B 4 pairs of propenylbenzene amido quinazoline derivatives and its application in antineoplastic is prepared 陕西师范大学 2017-10-27 CN disclosed
CN-105017162-A 4-P-propenylphenylaminoquinazoline derivative and application thereof in preparation of antitumor drugs UNIV SHAANXI NORMAL 2015-11-04 CN disclosed
EP-0918503-A4 HAIR COLORING COMPOSITIONS PROCTER & GAMBLE (US) 2000-07-12 EP disclosed
EP-0918503-A1 HAIR COLORING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1999-06-02 EP disclosed
EP-0691966-B1 QUINOLINES AS TYPE IV PHOSPHODIESTERASE INHIBITORS SYNTEX INC (US) 1998-09-09 EP disclosed
WO-1997024105-A1 HAIR COLORING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1997-07-10 WO disclosed
EP-0691966-A1 QUINOLINES AS TYPE IV PHOSPHODIESTERASE INHIBITORS SYNTEX (U.S.A.) INC. (US) 1996-01-17 EP disclosed
US-5455252-A Antiinflammatory agent, immunosuppressant, antiallergen, skin disorders, bronchodilator, analgesic SYNTEX (U.S.A.) INC. (US) 1995-10-03 US disclosed
WO-1994022852-A1 QUINOLINES AS TYPE IV PHOSPHODIESTERASE INHIBITORS SYNTEX (U.S.A.) INC. (US) 1994-10-13 WO disclosed
EP-0587243-A1 Thermoplastic polymer composition DSM N.V. (NL) 1994-03-16 EP disclosed
EP-0104863-B1 LIGHT-SENSITIVE PLANOGRAPHIC PRINTING PLATE FUJI PHOTO FILM CO., LTD. (JP) 1989-05-03 EP disclosed