SCHEMBL333123

SCHEMBL333123

CC=Cc1ccc(C=CC)cc1

nearest known ligand 0.65

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.65
LMNA P02545 1/20 0.65
TP53 P04637 1/20 0.65
TSHR P16473 1/20 0.65
KDM4E B2RXH2 1/20 0.65
ALDH1A1 P00352 1/20 0.65
CNR2 P34972 1/20 0.52
ATM Q13315 1/20 0.46
TYR P14679 1/20 0.44
NFE2L2 Q16236 1/20 0.39
APP P05067 4/20 0.38
RELA Q04206 2/20 0.36
APLNR P35414 1/20 0.36
TRPA1 O75762 1/20 0.36
CA1 P00915 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7527708 1.00 CYP3A4 (0.65) CYP3A4LMNATP53TSHRKDM4E
SCHEMBL9461723 1.00 CYP3A4 (0.65) CYP3A4LMNATP53TSHRKDM4E
SCHEMBL29982274 0.90 CYP3A4 (0.56) CYP3A4LMNATP53TSHRKDM4E
SCHEMBL272755 0.87 NFE2L2 (0.56) CYP3A4LMNATP53TSHRKDM4E
SCHEMBL272756 0.87 NFE2L2 (0.56) CYP3A4LMNATP53TSHRKDM4E
SCHEMBL840235 0.87 NFE2L2 (0.56) CYP3A4LMNATP53TSHRKDM4E
SCHEMBL1394423 0.85 ALDH1A1 (0.52) CYP3A4LMNATP53TSHRKDM4E
SCHEMBL16234246 0.85 CYP3A4 (0.52) CYP3A4LMNATP53TSHRKDM4E
SCHEMBL555296 0.85 APP (0.59) CYP3A4LMNATP53TSHRKDM4E
SCHEMBL597516 0.85 APP (0.59) CYP3A4LMNATP53TSHRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 309 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240307332-A1 COMPOSITIONS AND METHODS FOR MODULATING HEXIM1 EXPRESSION UNIV CASE WESTERN RESERVE (US) 2024-09-19 US claimed
CN-118472393-A Sodium ion battery electrolyte, preparation method thereof, sodium ion battery and power utilization device 江苏天合储能有限公司 2024-08-09 CN claimed
US-11833124-B2 Compositions and methods for modulating HEXIM1 expression CASE WESTERN RESERVE UNIVERSITY (US) 2023-12-05 US claimed
US-20220355285-A1 CATALYST FOR ALKYLENE OXIDE ADDITION REACTION AND APPLICATION THEREOF CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2022-11-10 US claimed
EP-4035772-A1 CATALYST FOR ALKYLENE OXIDE ADDITION REACTION AND APPLICATION THEREOF China Petroleum & Chemical Corporation (CN) 2022-08-03 EP claimed
US-20210212969-A1 COMPOSITIONS AND METHODS FOR MODULATING HEXIM1 EXPRESSION CLEVELAND STATE UNIVERSITY 2021-07-15 US claimed
WO-2021057835-A1 CATALYST FOR ALKYLENE OXIDE ADDITION REACTION AND APPLICATION THEREOF 中国石油化工股份有限公司 2021-04-01 WO claimed
CN-112079886-A Method for improving purity of xylose and arabinose by chromatographic separation 甘肃赫原生物制品有限公司 2020-12-15 CN claimed
CN-106463706-B Method for manufacturing electrode 宇部兴产株式会社 2019-06-18 CN claimed
CN-106165164-B Method for manufacturing electrode 宇部兴产株式会社 2019-01-22 CN claimed
WO-2009058373-A2 HALO-FUNCTIONAL SILANE, PROCESS FOR ITS PREPARATION, RUBBER COMPOSITION CONTAINING SAME AND ARTICLES MANUFACTURED THEREFROM MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2009-05-07 WO claimed
US-20090111923-A1 Halo-functional silane, process for its preparation, rubber composition containing same and articles manufactured therefrom MOMENTIVE PERFORMANCE MATERIALS INC. 2009-04-30 US claimed
US-7368584-B2 Mercapto-functional silane MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2008-05-06 US claimed
WO-2008021308-A2 MERCAPTO-FUNCTIONAL SILANE COMPOSITIONS HAVING REDUCED VOC LEVELS MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2008-02-21 WO claimed
US-20080039645-A1 Mercapto-functional silane GENERAL ELECTRIC COMPANY (US) 2008-02-14 US claimed
US-7138537-B2 Coupling agents for mineral-filled elastomer compositions GENERAL ELECTRIC COMPANY (US) 2006-11-21 US claimed
US-20060217474-A1 Coupling agents for mineral-filled elastomer compositions CRUSE RICHARD W 2006-09-28 US claimed
EP-1613636-A1 COUPLING AGENTS FOR MINERAL-FILLED ELASTOMER COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 2006-01-11 EP claimed
WO-2004094437-A1 COUPLING AGENTS FOR MINERAL-FILLED ELASTOMER COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 2004-11-04 WO claimed
US-20040198881-A1 Coupling agents for mineral-filled elastomer compositions CROMPTON CORPORATION 2004-10-07 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210212969-A1 COMPOSITIONS AND METHODS FOR MODULATING HEXIM1 EXPRESSION HK1, HKDC1, HEXB CYP3A4 3476/4885LMNA 3847/4885TP53 2463/4885
US-11833124-B2 Compositions and methods for modulating HEXIM1 expression HK1, HKDC1, HEXB CYP3A4 3476/4885LMNA 3847/4885TP53 2463/4885
US-20240307332-A1 COMPOSITIONS AND METHODS FOR MODULATING HEXIM1 EXPRESSION HK1, HKDC1, HEXB CYP3A4 3476/4885LMNA 3847/4885TP53 2463/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.