⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1929701 | 0.86 | — | — | |
| SCHEMBL596991 | 0.86 | — | — | |
| SCHEMBL9035339 | 0.83 | — | — | |
| SCHEMBL251107 | 0.83 | — | — | |
| SCHEMBL3300189 | 0.78 | — | — | |
| SCHEMBL4556780 | 0.78 | — | — | |
| SCHEMBL3398837 | 0.78 | — | — | |
| SCHEMBL11053845 | 0.71 | ALDH1A1 (0.46) | — | |
| SCHEMBL4556493 | 0.69 | — | — | |
| SCHEMBL7800087 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 460 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3743430-B1 | AMINOPYRROLOTRIAZINES AS KINASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2023-08-02 | — | — | EP | claimed |
| US-11643438-B2 | Antimicrobial peptides and methods of use | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) | 2023-05-09 | — | — | US | claimed |
| CN-109336845-B | Optically active cyclopentane-3-imine and its derivative and preparation method | 西华师范大学 | 2022-11-01 | — | — | CN | claimed |
| CN-114478429-A | 3-alkylthio isothiazole derivative and synthetic method thereof | 中国科学院大连化学物理研究所 | 2022-05-13 | — | — | CN | claimed |
| EP-3965884-A1 | MODULATORS OF THR-BETA AND METHODS OF USE THEREOF | Aligos Therapeutics, Inc. (US) | 2022-03-16 | — | — | EP | claimed |
| CN-114044753-A | Small molecular compound with anti-tumor metastasis function and preparation method thereof | 广州市朝利良生物科技有限公司 | 2022-02-15 | — | — | CN | claimed |
| CN-113952295-A | Anti-tumor metastasis medicine and application thereof | 广州市朝利良生物科技有限公司 | 2022-01-21 | — | — | CN | claimed |
| CN-113896662-A | Amino cyclopropane carboxylic acid compound and preparation method and application thereof | 五邑大学 | 2022-01-07 | — | — | CN | claimed |
| CN-113754635-A | Fused ring compound and preparation method and application thereof | 成都康弘药业集团股份有限公司 | 2021-12-07 | — | — | CN | claimed |
| US-20210317167-A1 | ANTIMICROBIAL PEPTIDES AND METHODS OF USE | UNIV OKLAHOMA (US) | 2021-10-14 | — | — | US | claimed |
| US-6509338-B1 | Psychiatric disorders and neurological diseases including affective disorder, anxiety, depression, headache, irritable bowel syndrome, post-traumatic stress disorder, supranuclear palsy, immune suppression, Alzheimer's disease, | BRISTOL-MYERS SQUIBB COMPANY | 2003-01-21 | — | — | US | claimed |
| EP-1187615-A2 | IMMUNOSURPRESSIVE EFFECTS OF PTERIDINE DERIVATIVES | K.U. Leuven Research & Development (BE) | 2002-03-20 | — | — | EP | claimed |
| WO-2000045800-A2 | IMMUNOSURPRESSIVE EFFECTS OF PTERIDINE DERIVATIVES | K.U. LEUVEN RESEARCH & DEVELOPMENT (BE) | 2000-08-10 | — | — | WO | claimed |
| US-5763627-A | Process for preparing cyclopropyl alkyl ketones and 4,5-dihydroalkyfurans | HUELS AKTIENGESELLSCHAFT (DE) | 1998-06-09 | — | — | US | claimed |
| CN-1022409-C | Liquid crystal cyclicpropylalkyl or alkenyl heterocyclic compound and process for preparing same | HOECHST AG (DE) | 1993-10-13 | — | — | CN | claimed |
| CN-1017897-B | DIHYDROPYRIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE | SANKYO CO (JP) | 1992-08-19 | — | — | CN | claimed |
| WO-1991012206-A2 | AROMATASE-INHIBITING STEROIDS | ENDORECHERCHE INC. (CA) | 1991-08-22 | — | — | WO | claimed |
| CN-1039019-A | Liquid crystal cyclopropyl alkyl or alkenyl heterogeneous ring compound, its preparation method and the application in liquid crystal compound | HOECHST AG (DE) | 1990-01-24 | — | — | CN | claimed |
| EP-0091755-A1 | Penicillin derivatives, a process for their preparation and compositions containing them | BEECHAM GROUP PLC (GB) | 1983-10-19 | — | — | EP | claimed |
| EP-0067612-A1 | Penicillin derivatives | BEECHAM GROUP PLC (GB) | 1982-12-22 | — | — | EP | claimed |