Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | KCNA5 | P22460 | 5/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 5/20 | 0.43 |
| ▸ | KCND2 | Q9NZV8 | 5/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2957032 | 0.96 | SLC6A4 (0.43) | SLC6A4KCNA5SCN5AKCND2KCNH2 | |
| SCHEMBL2960049 | 0.92 | SLC6A4 (0.51) | SLC6A4KCNA5SCN5AKCND2KCNH2 | |
| SCHEMBL2632456 | 0.75 | SLC6A4 (0.55) | SLC6A4KCNA5SCN5AKCND2KCNH2 | |
| Hydrochloric Acid SCHEMBL1762230 | 0.74 | KCNA5 (0.56) | SLC6A4KCNA5SCN5AKCND2KCNH2 | |
| SCHEMBL2632591 | 0.72 | MEN1 (0.57) | ATMKDM4EMEN1KMT2AEPHX1 | |
| SCHEMBL10343404 | 0.72 | ATM (0.70) | ATMKDM4EKMT2ASIGMAR1POLB | |
| SCHEMBL30869991 | 0.72 | ATM (0.70) | ATMKDM4EKMT2ASIGMAR1POLB | |
| SCHEMBL2624902 | 0.72 | SLC6A4 (0.62) | SLC6A4KCNA5SCN5AKCND2KCNH2 | |
| SCHEMBL1762363 | 0.72 | SLC6A4 (0.62) | SLC6A4KCNA5SCN5AKCND2KCNH2 | |
| SCHEMBL3586935 | 0.72 | SLC6A4 (0.62) | SLC6A4KCNA5SCN5AKCND2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1560812-B1 | AMINOCYCLOHEXYL ETHER COMPOUNDS AND USES THEREOF | CARDIOME PHARMA CORP (CA) | 2006-05-10 | — | — | EP | disclosed |