Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 11/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.57 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23127778 | 1.00 | DNM1 (0.57) | DNM1TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL21090070 | 1.00 | DNM1 (0.57) | DNM1TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL20957449 | 1.00 | DNM1 (0.57) | DNM1TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL5703951 | 1.00 | DNM1 (0.57) | DNM1TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL16186286 | 1.00 | DNM1 (0.57) | DNM1TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL21090668 | 0.98 | DNM1 (0.55) | DNM1TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL25844944 | 0.98 | DNM1 (0.55) | DNM1TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL25844886 | 0.98 | DNM1 (0.55) | DNM1TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL6350676 | 0.97 | DNM1 (0.60) | DNM1TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL3793709 | 0.97 | DNM1 (0.60) | DNM1TSHRMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7067697-B2 | Cationic liposomes for gene transfer | VANDERBILT UNIVERSITY (US) | 2006-06-27 | — | — | US | disclosed |
| US-20060057194-A1 | Cationic liposomes for gene transfer | GAO XIANG | 2006-03-16 | — | — | US | disclosed |
| US-7002042-B2 | Cationic liposomes for gene transfer | VANDERBILT UNIVERSITY (US) | 2006-02-21 | — | — | US | disclosed |
| US-6656498-B1 | Cationic liposomes for gene transfer | VANDERBILT UNIVERSITY | 2003-12-02 | — | — | US | disclosed |
| US-20030049310-A1 | Cationic liposomes for gene transfer | VANDERBILT UNIVERSITY | 2003-03-13 | — | — | US | disclosed |
| WO-2000030444-A1 | CATIONIC LIPOSOMES FOR GENE TRANSFER | VANDERBILT UNIVERSITY (US) | 2000-06-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060057194-A1 | Cationic liposomes for gene transfer | LCLAT1, LPCAT3, LPCAT1 | DNM1 778/4885TSHR 3205/4885MEN1 2064/4885 |
| US-20030049310-A1 | Cationic liposomes for gene transfer | LCLAT1, LPCAT3, LPCAT1 | DNM1 778/4885TSHR 3205/4885MEN1 2064/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.