SCHEMBL598142

SCHEMBL598142

CC1CCc2ccccc2C1

nearest known ligand 0.56

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PLAU P00749 1/20 0.56
MTNR1A P48039 2/20 0.47
MTNR1B P49286 2/20 0.47
HTR1A P08908 1/20 0.47
ANPEP P15144 1/20 0.47
MAOA P21397 1/20 0.46
MAOB P27338 1/20 0.46
GRIN2B Q13224 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
TSHR P16473 1/20 0.42
CYP19A1 P11511 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29978110 1.00 PLAU (0.56) PLAUMTNR1AMTNR1BHTR1AANPEP
SCHEMBL15147099 1.00 PLAU (0.56) PLAUMTNR1AMTNR1BHTR1AANPEP
SCHEMBL11863282 0.98 PLAU (0.54) PLAUMTNR1AMTNR1BHTR1AANPEP
SCHEMBL15888992 0.86 TSHR (0.50) PLAUMTNR1AMTNR1BHTR1ATSHR
SCHEMBL315647 0.82 BRD4 (0.54) PLAUTSHR
Methane SCHEMBL27448869 0.79 BRD4 (0.52) PLAUTSHR
SCHEMBL597327 0.77 CYP2A6 (0.41) TSHR
SCHEMBL11145661 0.77 DGAT1 (0.47)
SCHEMBL7712799 0.76 CYP2A6 (0.50) MAOAMAOBTSHRCYP19A1
SCHEMBL5124383 0.76 CHRM3 (0.41) PLAU

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109929328-B Composite ink and preparation method and device thereof TCL科技集团股份有限公司 2021-10-22 CN claimed
US-20200373508-A1 ELECTROLUMINESCENT MATERIAL INK AND ELECTROLUMINESCENT DEVICE THEREOF GUANGDONG JUHUA PRINTED DISPLAY TECHNOLOGY CO., LTD. (CN) 2020-11-26 US claimed
CN-108948865-B Electroluminescent material ink and electroluminescent device thereof 广东聚华印刷显示技术有限公司 2020-07-10 CN claimed
CN-109929328-A A kind of compound ink and preparation method thereof, device TCL集团股份有限公司 2019-06-25 CN claimed
CN-108948865-A Electroluminescent material ink and its electroluminescent device 广东聚华印刷显示技术有限公司 2018-12-07 CN claimed
WO-2000012082-A1 FORMAMIDE COMPOUNDS AS THERAPEUTIC AGENTS GLAXO GROUP LIMITED (GB) 2000-03-09 WO claimed
EP-0160508-B1 PHENOL DERIVATIVES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1989-05-31 EP claimed
JP-2255627-A None JP disclosed
JP-63002942-A None JP disclosed
EP-3360175-B1 FORMULATIONS COMPRISING AT LEAST TWO ORGANIC SEMICONDUCTING COMPOUNDS AND AT LEAST TWO SOLVENTS MERCK PATENT GMBH (DE) 2023-05-17 EP disclosed
US-11637257-B2 Electroluminescent material ink and electroluminescent device thereof GUANGDONG JUHUA PRINTED DISPLAY TECHNOLOGY CO. LTD (CN) 2023-04-25 US disclosed
US-20220402915-A1 BCL-2 INHIBITORS BEONE MEDICINES I GMBH (CH) 2022-12-22 US disclosed
EP-3131897-B1 FACTOR IXA INHIBITORS MERCK SHARP & DOHME (US) 2022-06-15 EP disclosed
EP-0058633-B1 COMPOSITION CONTAINING AN ABRASIVE SUBSTRATE FOR THE CLEANING OF HARD SURFACES Airwick AG (CH) 1984-12-27 EP disclosed
EP-0036833-B1 PROCESS FOR THE CLEANING OF TEXTIL MATERIAL Airwick AG (CH) 1984-04-11 EP disclosed
EP-0058633-A1 Composition containing an abrasive substrate for the cleaning of hard surfaces Airwick AG (CH) 1982-08-25 EP disclosed
US-4336024-A USING ORGANIC SOLVENTS AIRWICK INDUSTRIES, INC. (US) 1982-06-22 US disclosed
US-4334977-A HYDROGEN DONOR SOLVENT AND HYDROGEN TRANSFER SOLVENT MOBIL OIL CORPORATION (US) 1982-06-15 US disclosed
EP-0036833-A1 Process for the cleaning of textil material Airwick AG (CH) 1981-09-30 EP disclosed
US-4276305-A INSECTICIDES, MITICIDES HOFFMANN-LA ROCHE INC. (US) 1981-06-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220402915-A1 BCL-2 INHIBITORS BCL2, BCL2L1, BCL2L2 PLAU 4258/4885MTNR1A 3876/4885MTNR1B 3204/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.