SCHEMBL5981809

SCHEMBL5981809

CCCCCCCCCCCCCCCCCCN(CCC)CCCCCCCCCCCCCCCCCC

nearest known ligand 0.55

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 4/20 0.55
TSHR P16473 1/20 0.50
THRB P10828 1/20 0.50
KDM5A P29375 2/20 0.42
PHF8 Q9UPP1 2/20 0.42
KDM4C Q9H3R0 1/20 0.42
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA9 Q16790 1/20 0.42
KCNH2 Q12809 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL627757 1.00 DNM1 (0.55) DNM1TSHRTHRBKDM5APHF8
SCHEMBL116822 1.00 DNM1 (0.55) DNM1TSHRTHRBKDM5APHF8
SCHEMBL20711482 1.00 DNM1 (0.55) DNM1TSHRTHRBKDM5APHF8
SCHEMBL24372535 1.00 DNM1 (0.55) DNM1TSHRTHRBKDM5APHF8
SCHEMBL4891576 1.00 DNM1 (0.55) DNM1TSHRTHRBKDM5APHF8
SCHEMBL24473984 1.00 DNM1 (0.55) DNM1TSHRTHRBKDM5APHF8
SCHEMBL24113636 1.00 DNM1 (0.55) DNM1TSHRTHRBKDM5APHF8
SCHEMBL24728617 1.00 DNM1 (0.55) DNM1TSHRTHRBKDM5APHF8
SCHEMBL20979308 1.00 DNM1 (0.55) DNM1TSHRTHRBKDM5APHF8
SCHEMBL14839985 1.00 DNM1 (0.55) DNM1TSHRTHRBKDM5APHF8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116348084-A Cosmetic compositions, kits, and methods of making and using the same 莱雅公司 2023-06-27 CN disclosed
CN-116018127-A Cosmetic compositions, kits, and methods of making and using the same 莱雅公司 2023-04-25 CN disclosed
CN-113301965-A Hair care system, hair care method and use of hair care system 欧莱雅 2021-08-24 CN disclosed
CN-113271917-A Hair care and conditioning composition 莱雅公司 2021-08-17 CN disclosed
US-20140170175-A1 NOVEL LIPIDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF BIOLOGICALLY ACTIVE COMPOUNDS AXOLABS GMBH (DE) 2014-06-19 US disclosed
US-20140170175-A1 NOVEL LIPIDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF BIOLOGICALLY ACTIVE COMPOUNDS AXOLABS GMBH (DE) 2014-06-19 US disclosed
US-20120295832-A1 Novel Lipids and Compositions for Intracellular Delivery of Biologically Active Compounds ARROWHEAD RESEARCH CORPORATION (US) 2012-11-22 US disclosed
US-20120295832-A1 Novel Lipids and Compositions for Intracellular Delivery of Biologically Active Compounds ARROWHEAD RESEARCH CORPORATION (US) 2012-11-22 US disclosed
US-7067697-B2 Cationic liposomes for gene transfer VANDERBILT UNIVERSITY (US) 2006-06-27 US disclosed
US-20060057194-A1 Cationic liposomes for gene transfer GAO XIANG 2006-03-16 US disclosed
US-7002042-B2 Cationic liposomes for gene transfer VANDERBILT UNIVERSITY (US) 2006-02-21 US disclosed
US-6656498-B1 Cationic liposomes for gene transfer VANDERBILT UNIVERSITY 2003-12-02 US disclosed
US-20030049310-A1 Cationic liposomes for gene transfer VANDERBILT UNIVERSITY 2003-03-13 US disclosed
WO-2000030444-A1 CATIONIC LIPOSOMES FOR GENE TRANSFER VANDERBILT UNIVERSITY (US) 2000-06-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060057194-A1 Cationic liposomes for gene transfer LCLAT1, LPCAT3, LPCAT1 DNM1 778/4885TSHR 3205/4885THRB 2303/4885
US-20140170175-A1 NOVEL LIPIDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF BIOLOGICALLY ACTIVE COMPOUNDS PHOSPHO1, NPC1L1, PLIN3 DNM1 408/4885TSHR 4444/4885THRB 3881/4885
US-20120295832-A1 Novel Lipids and Compositions for Intracellular Delivery of Biologically Active Compounds PHOSPHO1, NPC1L1, PLIN3 DNM1 408/4885TSHR 4444/4885THRB 3881/4885
US-20030049310-A1 Cationic liposomes for gene transfer LCLAT1, LPCAT3, LPCAT1 DNM1 778/4885TSHR 3205/4885THRB 2303/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.