Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4288356 | 0.90 | CNR2 (0.38) | CNR2HPGDLMNAPOLBMAPT | |
| SCHEMBL3555926 | 0.78 | HPGD (0.53) | HPGDLMNAPOLBMAPTNPSR1 | |
| SCHEMBL3547635 | 0.78 | HPGD (0.53) | HPGDLMNAPOLBMAPTNPSR1 | |
| SCHEMBL3547004 | 0.78 | HPGD (0.53) | HPGDLMNAPOLBMAPTNPSR1 | |
| SCHEMBL3548660 | 0.75 | CNR2 (0.44) | CNR2HPGDLMNAPOLBMAPT | |
| SCHEMBL4573986 | 0.73 | NAAA (0.43) | HPGDLMNAPOLBL3MBTL1ALDH1A1 | |
| SCHEMBL3546909 | 0.71 | PTGS1 (0.58) | HPGDLMNAPOLBMAPTNPSR1 | |
| SCHEMBL13817414 | 0.65 | CYP2C9 (0.45) | HPGDLMNAPOLBNPSR1L3MBTL1 | |
| SCHEMBL8554153 | 0.64 | HPGD (0.46) | HPGDLMNAPOLBL3MBTL1ALDH1A1 | |
| SCHEMBL3547218 | 0.62 | POLB (0.58) | HPGDLMNAPOLBMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1692121-A1 | THIAZOLIDINONE AMIDES, THIAZOLIDINE CARBOXYLIC ACID AMIDES, METHODS OF MAKING, AND USES THEREOF | University of Tennessee Research Foundation (US) | 2006-08-23 | — | — | EP | disclosed |
| WO-2005049591-A1 | THIAZOLIDINONE AMIDES, THIAZOLIDINE CARBOXYLIC ACID AMIDES, METHODS OF MAKING, AND USES THEREOF | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2005-06-02 | — | — | WO | disclosed |