Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5983758 | 0.91 | HRH4 (0.31) | HRH4HRH3 | |
| Trifluoroacetic Acid SCHEMBL5982636 | 0.90 | HRH4 (0.30) | HRH4HRH3 | |
| SCHEMBL13783369 | 0.82 | PARP1 (0.35) | — | |
| Hydrochloric Acid SCHEMBL4334320 | 0.81 | AURKA (0.34) | — | |
| SCHEMBL5992412 | 0.78 | PLD2 (0.34) | — | |
| SCHEMBL3944968 | 0.77 | PIK3CD (0.30) | — | |
| SCHEMBL4331632 | 0.76 | MAP3K7 (0.31) | — | |
| SCHEMBL4339148 | 0.74 | MAP3K7 (0.31) | — | |
| Hydrochloric Acid SCHEMBL4331991 | 0.74 | MAP3K7 (0.31) | — | |
| SCHEMBL3938534 | 0.73 | KDM4E (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1661896-A1 | PYRROLOPYRIMIDINETHIONE DERIVATIVE | Teijin Pharma Limited (JP) | 2006-05-31 | — | — | EP | disclosed |
| US-20050153992-A1 | Pyrrolopyrimidine thion derivatives | TEIJIN PHARMA LIMITED (JP) | 2005-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050153992-A1 | Pyrrolopyrimidine thion derivatives | GSK3B, GSK3A, GSKIP | HRH4 140/4885HRH3 178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.