Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 2/20 | 0.49 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.49 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4989634 | 0.90 | AKR1C3 (0.50) | AKR1C3TSHRKCNH2CA1CA2 | |
| SCHEMBL735219 | 0.86 | AKR1C3 (0.61) | AKR1C3TSHRKCNH2CA1CA2 | |
| SCHEMBL4989626 | 0.86 | AKR1C3 (0.53) | AKR1C3TSHRKCNH2CA1CA2 | |
| SCHEMBL14029262 | 0.85 | ACHE (0.50) | AKR1C3TSHRKCNH2CA1CA2 | |
| SCHEMBL27339909 | 0.83 | AKR1C3 (0.58) | AKR1C3TSHRKCNH2CA1CA2 | |
| SCHEMBL5983768 | 0.81 | AKR1C3 (0.74) | AKR1C3TSHRCA1CA2BCHE | |
| SCHEMBL4985770 | 0.81 | TSHR (0.58) | AKR1C3TSHRKCNH2ACHEIDO1 | |
| SCHEMBL14204632 | 0.81 | ACHE (0.53) | AKR1C3TSHRKCNH2CA1CA2 | |
| SCHEMBL3656180 | 0.81 | TSHR (0.62) | AKR1C3TSHRKCNH2IDO1KCNJ1 | |
| SCHEMBL14047521 | 0.81 | AKR1C3 (0.45) | AKR1C3TSHRKCNH2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9201067-B2 | Size-controlled macromolecule | POSCO (KR) | 2015-12-01 | — | — | US | disclosed |
| EP-1664341-B1 | SIZE-CONTROLLED MACROMOLECULE | POSCO (KR) | 2013-01-30 | — | — | EP | disclosed |
| EP-1664341-A2 | SIZE-CONTROLLED MACROMOLECULE | Posco (KR) | 2006-06-07 | — | — | EP | disclosed |
| WO-2005026191-A2 | SIZE-CONTROLLED MACROMOLECULE | POSCO (KR) | 2005-03-24 | — | — | WO | disclosed |
| US-20050037413-A1 | functionalized substrates bound to layers of dendrimers and to target-specific ligands, used in combinatorial chemistry, protein, nucleic acid or nucleic acid/peptide hybridization detection; medical diagnosis | POSCO (KR) | 2005-02-17 | — | — | US | disclosed |
| US-5039796-A | Process for 5'-phosphorylation of nucleic acids | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-08-13 | — | — | US | disclosed |