Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.45 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.45 |
| ▸ | UBE2N | P61088 | 1/20 | 0.45 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.45 |
| ▸ | YAP1 | P46937 | 2/20 | 0.44 |
| ▸ | CASP3 | P42574 | 4/20 | 0.42 |
| ▸ | PSMB11 | A5LHX3 | 3/20 | 0.41 |
| ▸ | PSMA7 | O14818 | 3/20 | 0.41 |
| ▸ | PSMB1 | P20618 | 3/20 | 0.41 |
| ▸ | PSMA1 | P25786 | 3/20 | 0.41 |
| ▸ | PSMA2 | P25787 | 3/20 | 0.41 |
| ▸ | PSMA3 | P25788 | 3/20 | 0.41 |
| ▸ | PSMA4 | P25789 | 3/20 | 0.41 |
| ▸ | PSMB8 | P28062 | 3/20 | 0.41 |
| ▸ | PSMB9 | P28065 | 3/20 | 0.41 |
| ▸ | PSMA5 | P28066 | 3/20 | 0.41 |
| ▸ | PSMB4 | P28070 | 3/20 | 0.41 |
| ▸ | PSMB6 | P28072 | 3/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23230085 | 1.00 | MAPK1 (0.45) | MAPK1ITGB1ITGA4UBE2NITGB7 | |
| SCHEMBL20815350 | 1.00 | MAPK1 (0.45) | MAPK1ITGB1ITGA4UBE2NITGB7 | |
| SCHEMBL29371746 | 1.00 | MAPK1 (0.45) | MAPK1ITGB1ITGA4UBE2NITGB7 | |
| SCHEMBL6840497 | 1.00 | MAPK1 (0.45) | MAPK1ITGB1ITGA4UBE2NITGB7 | |
| SCHEMBL4648918 | 0.99 | MAPK1 (0.44) | MAPK1ITGB1ITGA4UBE2NITGB7 | |
| SCHEMBL24868206 | 0.95 | ITGB1 (0.50) | MAPK1ITGB1ITGA4ITGB7YAP1 | |
| Potassium Ion SCHEMBL4648916 | 0.94 | UBE2N (0.41) | MAPK1ITGB1ITGA4UBE2NITGB7 | |
| SCHEMBL3744009 | 0.92 | MAPK1 (0.44) | MAPK1ITGB1ITGA4UBE2NITGB7 | |
| SCHEMBL22023402 | 0.92 | MAPK1 (0.44) | MAPK1ITGB1ITGA4UBE2NITGB7 | |
| SCHEMBL6480786 | 0.92 | MAPK1 (0.44) | MAPK1ITGB1ITGA4UBE2NITGB7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 644 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6867192-B1 | Compounds useful in the treatment of inflammatory diseases | GLAXO GROUP LIMITED (GB) | 2005-03-15 | — | — | US | claimed |
| EP-1487417-A2 | DRY POWDER MEDICAMENT FORMULATIONS | GLAXO GROUP LIMITED (GB) | 2004-12-22 | — | — | EP | claimed |
| US-20040241232-A1 | Dry powder medicament formulations | GLAXO GROUP LIMITED (GB) | 2004-12-02 | — | — | US | claimed |
| EP-1140837-B1 | COMPOUNDS USEFUL IN THE TREATMENT OF INFLAMMATORY DISEASES | GLAXO GROUP LTD (GB) | 2004-08-18 | — | — | EP | claimed |
| US-20040091407-A1 | Novel process for preparing crystalline particles | SMITHKLINE BEECHAM CORPORATION | 2004-05-13 | — | — | US | claimed |
| US-20040044035-A1 | Novel aqueous anti-inflammatory pharmaceutical formulation | SMITHKLINE BEECHAM CORPORATION | 2004-03-04 | — | — | US | claimed |
| US-20040039020-A1 | Inhalants comprising suspensions of (2S)-3-(4-(((4-(amino-carbonyl)-1-piperidinyl)carbonyl)oxy)phenyl)-2-((2-(2 -methyl phenoxy)acetyl)amino)pentanoyl)amino) propanoic acid and surfactants, used for prophylaxis of respiratory disorders | SMITHKLINE BEECHAM CORPORATION | 2004-02-26 | — | — | US | claimed |
| US-20040037784-A1 | Dry-powder pharmaceutical formulation for inhalation comprising alpha4-integrin antagonist | SMITHKLINE BEECHAM CORPORATION | 2004-02-26 | — | — | US | claimed |
| US-20040039021-A1 | Organic fluorine compounds as propellants having suspended particles of 3-(4-(((4-(aminocarbonyl)-1-piperidinyl)carbonyl) oxy)phenyl)-2-(((2S)-4-methyl-2-((2-(2-methylphenoxy)acetyl)am ino)pentanoyl)amino)propanoic acid, in cans; inhalants | SMITHKLINE BEECHAM CORPORATION | 2004-02-26 | — | — | US | claimed |
| US-20040034058-A1 | Novel pharmaceutical formulation suitable for nebulisation | SMITHKLINE BEECHAM CORPORATION | 2004-02-19 | — | — | US | claimed |
| WO-2002000200-A1 | NOVEL PROCESS FOR PREPARING CRYSTALLINE PARTICLES | GLAXO GROUP LIMITED (GB) | 2002-01-03 | — | — | WO | claimed |
| WO-2001095883-A1 | NOVEL PHARMACEUTICAL FORMULATION SUITABLE FOR NEBULISATION | GLAXO GROUP LIMITED (GB) | 2001-12-20 | — | — | WO | claimed |
| WO-2001095882-A1 | NOVEL AQUEOUS ANTI-INFLAMMATORY PHARMACEUTICAL FORMULATION | GLAXO GROUP LIMITED (GB) | 2001-12-20 | — | — | WO | claimed |
| WO-2001095925-A1 | PHARMACEUTICAL ANTI-INFLAMMATORY AEROSOL FORMULATION | GLAXO GROUP LIMITED (GB) | 2001-12-20 | — | — | WO | claimed |
| WO-2001095880-A1 | NOVEL PHARMACEUTICAL FORMULATION SUITABLE FOR NEBULISATION | GLAXO GROUP LIMITED (GB) | 2001-12-20 | — | — | WO | claimed |
| WO-2001095881-A1 | PHARMACEUTICAL ANTI-INFLAMMATORY AEROSOL FORMULATION | GLAXO GROUP LIMITED (GB) | 2001-12-20 | — | — | WO | claimed |
| WO-2001095879-A1 | NOVEL AQUEOUS ANTI-INFLAMMATORY PHARMACEUTICAL FORMULATION | GLAXO GROUP LIMITED (GB) | 2001-12-20 | — | — | WO | claimed |
| WO-2001095885-A1 | DRY-POWDER PHARMACEUTICAL FORMULATION FOR INHALATION COMPRISING ALPHA4-INTERGRIN ANTAGONIST | GLAXO GROUP LIMITED (GB) | 2001-12-20 | — | — | WO | claimed |
| EP-1140837-A1 | COMPOUNDS USEFUL IN THE TREATMENT OF INFLAMMATORY DISEASES | GLAXO GROUP LIMITED (GB) | 2001-10-10 | — | — | EP | claimed |
| WO-2000037444-A1 | COMPOUNDS USEFUL IN THE TREATMENT OF INFLAMMATORY DISEASES | GLAXO GROUP LIMITED (GB) | 2000-06-29 | — | — | WO | claimed |