Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | UBE2N | P61088 | 1/20 | 0.44 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.44 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.44 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 3/20 | 0.44 |
| ▸ | CASP3 | P42574 | 3/20 | 0.44 |
| ▸ | CASP7 | P55210 | 3/20 | 0.44 |
| ▸ | CASP6 | P55212 | 3/20 | 0.44 |
| ▸ | CASP8 | Q14790 | 3/20 | 0.44 |
| ▸ | YAP1 | P46937 | 2/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PSMB11 | A5LHX3 | 3/20 | 0.41 |
| ▸ | PSMA7 | O14818 | 3/20 | 0.41 |
| ▸ | PSMB1 | P20618 | 3/20 | 0.41 |
| ▸ | PSMA1 | P25786 | 3/20 | 0.41 |
| ▸ | PSMA2 | P25787 | 3/20 | 0.41 |
| ▸ | PSMA3 | P25788 | 3/20 | 0.41 |
| ▸ | PSMA4 | P25789 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22023402 | 1.00 | MAPK1 (0.44) | MAPK1UBE2NITGB1ITGA4ITGB7 | |
| SCHEMBL598356 | 0.92 | MAPK1 (0.45) | MAPK1UBE2NITGB1ITGA4ITGB7 | |
| SCHEMBL20815350 | 0.92 | MAPK1 (0.45) | MAPK1UBE2NITGB1ITGA4ITGB7 | |
| SCHEMBL6840497 | 0.92 | MAPK1 (0.45) | MAPK1UBE2NITGB1ITGA4ITGB7 | |
| SCHEMBL29371746 | 0.92 | MAPK1 (0.45) | MAPK1UBE2NITGB1ITGA4ITGB7 | |
| SCHEMBL23230085 | 0.92 | MAPK1 (0.45) | MAPK1UBE2NITGB1ITGA4ITGB7 | |
| SCHEMBL4648918 | 0.91 | MAPK1 (0.44) | MAPK1UBE2NITGB1ITGA4ITGB7 | |
| SCHEMBL6480786 | 0.91 | MAPK1 (0.44) | MAPK1UBE2NITGB1ITGA4ITGB7 | |
| SCHEMBL6480951 | 0.90 | MAPK1 (0.47) | MAPK1UBE2NITGB1ITGA4ITGB7 | |
| SCHEMBL6481282 | 0.89 | ITGB1 (0.46) | MAPK1UBE2NITGB1ITGA4ITGB7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3662948-A1 | A DISPENSING DEVICE | GLAXO GROUP LIMITED (GB) | 2020-06-10 | — | — | EP | disclosed |
| CN-101853424-B | Actuation indicator for a dispensing device | GLAXO GROUP LTD | 2015-05-06 | — | — | CN | disclosed |
| US-8397714-B2 | Dispensing device | GLAXO GROUP LIMITED (GB) | 2013-03-19 | — | — | US | disclosed |
| EP-1922100-B1 | AN INHALER | GLAXO GROUP LTD (GB) | 2012-11-07 | — | — | EP | disclosed |
| US-8251056-B2 | Inhaler | GLAXO GROUP LIMITED (GB) | 2012-08-28 | — | — | US | disclosed |
| US-7832351-B2 | Actuation indicator for a dispensing device | GLAXO GROUP LIMITED (GB) | 2010-11-16 | — | — | US | disclosed |
| EP-1516283-B9 | ACTUATION INDICATOR FOR A DISPENSING DEVICE | GLAXO GROUP LTD (GB) | 2009-10-07 | — | — | EP | disclosed |
| US-20090229604-A1 | AN INHALER | GLAXO GROUP LIMITED (GB) | 2009-09-17 | — | — | US | disclosed |
| US-20090178673-A1 | Actuation Indicator for a Dispensing Device | GLAXO GROUP LIMITED (GB) | 2009-07-16 | — | — | US | disclosed |
| EP-2058754-A1 | Actuation indicator for a dispensing device | Glaxo Group Limited (GB) | 2009-05-13 | — | — | EP | disclosed |
| EP-1922100-A1 | AN INHALER | GLAXO GROUP LIMITED (GB) | 2008-05-21 | — | — | EP | disclosed |
| US-20080105253-A1 | Dispensing Device | GLAXO GROUP LIMITED (GB) | 2008-05-08 | — | — | US | disclosed |
| EP-1861145-A1 | INHALATION DEVICES | GLAXO GROUP LIMITED (GB) | 2007-12-05 | — | — | EP | disclosed |
| EP-1858573-A1 | INHALATION DEVICES | GLAXO GROUP LIMITED (GB) | 2007-11-28 | — | — | EP | disclosed |
| WO-2007031325-A1 | A CLOSURE FOR A DISPENSING DEVICE | GLAXO GROUP LIMITED (GB) | 2007-03-22 | — | — | WO | disclosed |
| WO-2007028992-A1 | AN INHALER | GLAXO GROUP LIMITED (GB) | 2007-03-15 | — | — | WO | disclosed |
| EP-1725285-A1 | A DISPENSING DEVICE | GLAXO GROUP LIMITED (GB) | 2006-11-29 | — | — | EP | disclosed |
| WO-2006097745-A1 | INHALATION DEVICES | GLAXO GROUP LIMITED (GB) | 2006-09-21 | — | — | WO | disclosed |
| WO-2006097747-A1 | INHALATION DEVICES | GLAXO GROUP LIMITED (GB) | 2006-09-21 | — | — | WO | disclosed |
| WO-2005087299-A1 | A DISPENSING DEVICE | GLAXO GROUP LIMITED (GB) | 2005-09-22 | — | — | WO | disclosed |