⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17600593 | 0.72 | — | — | |
| Methylethylamine SCHEMBL15561293 | 0.69 | — | — | |
| SCHEMBL3014495 | 0.67 | — | — | |
| Propane SCHEMBL1683354 | 0.66 | TSHR (0.36) | — | |
| SCHEMBL27338597 | 0.65 | ALDH1A1 (0.38) | — | |
| SCHEMBL15442498 | 0.65 | TSHR (0.32) | — | |
| SCHEMBL10887847 | 0.63 | — | — | |
| SCHEMBL19990 | 0.63 | — | — | |
| Butane SCHEMBL3799640 | 0.63 | TSHR (0.33) | — | |
| SCHEMBL16412187 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7071170-B2 | Macrolide antibiotics | PFIZER INC. (US) | 2006-07-04 | — | — | US | disclosed |
| US-20050004047-A1 | Novel macrolide antibiotics | PFIZER INC | 2005-01-06 | — | — | US | disclosed |
| US-6835716-B2 | Bactericides, antiprotozoa agents | PFIZER, INC. | 2004-12-28 | — | — | US | disclosed |
| US-20030013665-A1 | Novel macrolide antibiotics | PFIZER INC. | 2003-01-16 | — | — | US | disclosed |
| US-20020040007-A1 | Novel macrolide antibiotics | PFIZER PRODUCTS INC. | 2002-04-04 | — | — | US | disclosed |
| EP-1124837-A2 | NOVEL MACROLIDE ANTIBIOTICS | Pfizer Products Inc. (US) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000026224-A2 | NOVEL MACROLIDE ANTIBIOTICS | PFIZER PRODUCTS INC. (US) | 2000-05-11 | — | — | WO | disclosed |