Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 18/20 | 0.71 |
| ▸ | OPRM1 | P35372 | 15/20 | 0.71 |
| ▸ | OPRK1 | P41145 | 8/20 | 0.71 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5529656 | 0.96 | OPRD1 (0.76) | OPRD1OPRM1OPRK1KCNH2 | |
| SCHEMBL5526370 | 0.91 | OPRD1 (0.70) | OPRD1OPRM1OPRK1KCNH2 | |
| SCHEMBL5525378 | 0.88 | OPRD1 (0.68) | OPRD1OPRM1OPRK1KCNH2 | |
| SCHEMBL14417245 | 0.88 | OPRD1 (0.72) | OPRD1OPRM1OPRK1KCNH2 | |
| SCHEMBL5534085 | 0.86 | OPRD1 (0.66) | OPRD1OPRM1OPRK1KCNH2 | |
| SCHEMBL5529102 | 0.85 | OPRD1 (0.73) | OPRD1OPRM1OPRK1KCNH2 | |
| SCHEMBL5530276 | 0.84 | OPRD1 (0.76) | OPRD1OPRM1OPRK1KCNH2 | |
| SCHEMBL5879331 | 0.84 | OPRD1 (0.75) | OPRD1OPRM1OPRK1KCNH2 | |
| SCHEMBL5529675 | 0.84 | OPRD1 (0.71) | OPRD1OPRM1OPRK1KCNH2 | |
| SCHEMBL5526139 | 0.83 | OPRD1 (0.63) | OPRD1OPRM1OPRK1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1706379-A1 | DIARYLMETHYLIDENE PIPERIDINE DERIVATIVES, PREPARATIONS THEREOF AND USES THEREOF | AstraZeneca AB (SE) | 2006-10-04 | — | — | EP | claimed |
| WO-2005066127-A1 | DIARYLMETHYLIDENE PIPERIDINE DERIVATIVES, PREPARATIONS THEREOF AND USES THEREOF | ASTRAZENECA AB (SE) | 2005-07-21 | — | — | WO | claimed |