Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.30 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.30 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5985830 | 1.00 | ALDH1A1 (0.39) | ALDH1A1TDP1LMNACYP3A4TSHR | |
| SCHEMBL5984758 | 1.00 | ALDH1A1 (0.39) | ALDH1A1TDP1LMNACYP3A4TSHR | |
| SCHEMBL5985107 | 1.00 | ALDH1A1 (0.39) | ALDH1A1TDP1LMNACYP3A4TSHR | |
| SCHEMBL5985735 | 1.00 | ALDH1A1 (0.39) | ALDH1A1TDP1LMNACYP3A4TSHR | |
| SCHEMBL5987013 | 1.00 | ALDH1A1 (0.39) | ALDH1A1TDP1LMNACYP3A4TSHR | |
| SCHEMBL5985621 | 1.00 | ALDH1A1 (0.39) | ALDH1A1TDP1LMNACYP3A4TSHR | |
| SCHEMBL5983813 | 1.00 | ALDH1A1 (0.39) | ALDH1A1TDP1LMNACYP3A4TSHR | |
| SCHEMBL5985804 | 1.00 | ALDH1A1 (0.39) | ALDH1A1TDP1LMNACYP3A4TSHR | |
| SCHEMBL5984907 | 1.00 | ALDH1A1 (0.39) | ALDH1A1TDP1LMNACYP3A4TSHR | |
| SCHEMBL5984120 | 1.00 | ALDH1A1 (0.39) | ALDH1A1TDP1LMNACYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7018993-B2 | Antiandrogenic agent | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2006-03-28 | — | — | US | disclosed |
| US-20030158164-A1 | Novel antiandrogenic agent | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-08-21 | — | — | US | disclosed |
| EP-1304334-A1 | NOVEL ANTIANDROGENIC AGENT | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-04-23 | — | — | EP | disclosed |
| EP-1219631-A1 | ANTIANDROGEN AGENTS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2002-07-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030158164-A1 | Novel antiandrogenic agent | NR5A1, CYP19A1, HSD17B11 | ALDH1A1 399/4885TDP1 3394/4885LMNA 2182/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.