Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 8/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5399331 | 0.97 | CHRNA7 (0.42) | CHRNA7MEN1KMT2AATMHTR3A | |
| Formic Acid SCHEMBL2788520 | 0.86 | CHRNA7 (0.44) | CHRNA7MEN1KMT2AATMHTR3A | |
| Formic Acid SCHEMBL5986334 | 0.85 | CHRNA7 (0.43) | CHRNA7HTR3A | |
| Formic Acid SCHEMBL5985014 | 0.84 | CHRNA7 (0.42) | CHRNA7MEN1KMT2AATMHTR3A | |
| Formic Acid SCHEMBL5984989 | 0.84 | HTR3A (0.44) | CHRNA7MEN1KMT2AATMHTR3A | |
| SCHEMBL1964948 | 0.82 | CHRNA7 (0.47) | CHRNA7MEN1KMT2AATMHTR3A | |
| SCHEMBL5411048 | 0.82 | CHRNA7 (0.43) | CHRNA7MEN1KMT2AATMHTR3A | |
| Formic Acid SCHEMBL5993888 | 0.81 | CHRNA7 (0.45) | CHRNA7HTR3A | |
| SCHEMBL5400195 | 0.81 | CHRNA7 (0.46) | CHRNA7HTR3A | |
| SCHEMBL5407888 | 0.80 | HTR3A (0.47) | CHRNA7MEN1KMT2AATMHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1735306-A2 | INDAZOLES, BENZOTHIAZOLES, BENZOISOTHIAZOLES, BENZISOXAZOLES, AND PREPARATION AND USES THEREOF | Memory Pharmaceuticals Corporation (US) | 2006-12-27 | — | — | EP | disclosed |
| WO-2005092890-A2 | INDAZOLES, BENZOTHIAZOLES, BENZOISOTHIAZOLES, BENZISOXAZOLES, AND PREPARATION AND USES THEREOF | MEMORY PHARMACEUTICALS CORPORATION (US) | 2005-10-06 | — | — | WO | disclosed |