Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.30 |
| ▸ | STAT3 | P40763 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5985811 | 0.92 | TSHR (0.43) | NPC1ALDH1A1TSHRRAB9ASMN1; SMN2 | |
| SCHEMBL7792859 | 0.92 | NPC1 (0.43) | NPC1ALDH1A1TSHRRAB9ASMN1; SMN2 | |
| SCHEMBL13134778 | 0.86 | NPC1 (0.50) | NPC1ALDH1A1TSHRRAB9ASMN1; SMN2 | |
| SCHEMBL21449552 | 0.84 | NPC1 (0.49) | NPC1ALDH1A1TSHRRAB9ASMN1; SMN2 | |
| SCHEMBL7796314 | 0.81 | NPC1 (0.40) | NPC1ALDH1A1TSHRRAB9ASMN1; SMN2 | |
| SCHEMBL22262861 | 0.76 | — | — | |
| SCHEMBL20745048 | 0.76 | — | — | |
| SCHEMBL20745195 | 0.76 | — | — | |
| SCHEMBL16692536 | 0.73 | TSHR (0.53) | NPC1ALDH1A1TSHRRAB9ASMN1; SMN2 | |
| SCHEMBL20745102 | 0.72 | P2RX7 (0.39) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2447264-A1 | N-SUBSTITUTED-CYCLIC AMINO DERIVATIVE | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2012-05-02 | — | — | EP | disclosed |
| WO-2010150840-A1 | N-SUBSTITUTED-CYCLIC AMINO DERIVATIVE | 大日本住友製薬株式会社 (JP) | 2010-12-29 | — | — | WO | disclosed |