SCHEMBL5985329

SCHEMBL5985329

[CH2]CCCCC/C=C/CCC(CC)CCCCCCCCC[CH2]

nearest known ligand 0.37

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
FAAH O00519 2/20 0.32
TRPV1 Q8NER1 2/20 0.32
FFAR1 O14842 1/20 0.31
FFAR4 Q5NUL3 1/20 0.31
TRPM8 Q7Z2W7 1/20 0.30
MEN1 O00255 1/20 0.30
CYP3A4 P08684 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5984600 1.00 FAAH (0.32) FAAHTRPV1FFAR1FFAR4TRPM8
SCHEMBL5984596 1.00 FAAH (0.32) FAAHTRPV1FFAR1FFAR4TRPM8
SCHEMBL5985334 1.00 FAAH (0.32) FAAHTRPV1FFAR1FFAR4TRPM8
SCHEMBL5984909 1.00 FAAH (0.32) FAAHTRPV1FFAR1FFAR4TRPM8
SCHEMBL5986187 1.00 FAAH (0.32) FAAHTRPV1FFAR1FFAR4TRPM8
SCHEMBL5985787 1.00 FAAH (0.32) FAAHTRPV1FFAR1FFAR4TRPM8
SCHEMBL5984915 1.00 FAAH (0.32) FAAHTRPV1FFAR1FFAR4TRPM8
SCHEMBL5986185 1.00 FAAH (0.32) FAAHTRPV1FFAR1FFAR4TRPM8
SCHEMBL5985784 1.00 FAAH (0.32) FAAHTRPV1FFAR1FFAR4TRPM8
SCHEMBL5986251 0.96 FAAH (0.34) FAAHTRPV1FFAR1FFAR4TRPM8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7018993-B2 Antiandrogenic agent CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2006-03-28 US disclosed
US-20030158164-A1 Novel antiandrogenic agent CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2003-08-21 US disclosed
EP-1304334-A1 NOVEL ANTIANDROGENIC AGENT CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2003-04-23 EP disclosed
EP-1219631-A1 ANTIANDROGEN AGENTS CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2002-07-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030158164-A1 Novel antiandrogenic agent NR5A1, CYP19A1, HSD17B11 FAAH 1409/4885TRPV1 4436/4885FFAR1 240/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.