⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5857075 | 1.00 | — | — | |
| SCHEMBL3207594 | 0.93 | FAAH (0.32) | — | |
| SCHEMBL1677761 | 0.93 | — | — | |
| SCHEMBL5986741 | 0.93 | FAAH (0.32) | — | |
| SCHEMBL1677758 | 0.93 | — | — | |
| SCHEMBL5984414 | 0.89 | FAAH (0.36) | — | |
| SCHEMBL5984010 | 0.89 | FAAH (0.36) | — | |
| SCHEMBL5985121 | 0.89 | FAAH (0.36) | — | |
| SCHEMBL5984042 | 0.89 | FAAH (0.36) | — | |
| SCHEMBL5984843 | 0.89 | FAAH (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7018993-B2 | Antiandrogenic agent | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2006-03-28 | — | — | US | disclosed |
| US-20030158164-A1 | Novel antiandrogenic agent | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-08-21 | — | — | US | disclosed |
| EP-1304334-A1 | NOVEL ANTIANDROGENIC AGENT | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-04-23 | — | — | EP | disclosed |
| EP-1219631-A1 | ANTIANDROGEN AGENTS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2002-07-03 | — | — | EP | disclosed |
| EP-0836635-B1 | Compositions of synthetic polymers and a polysilane derivative | CIBA SC HOLDING AG (CH) | 2001-12-05 | — | — | EP | disclosed |
| US-6005036-A | ADDED TO ORGANIC MATERIAL TO PREVENT OXIDATIVE, THERMAL AND ACTINIC DEGRADATION | CIBA SPECIALTY CHEMICAL CORPORATION (US) | 1999-12-21 | — | — | US | disclosed |
| EP-0836635-A1 | Compositions of synthetic polymers and a polysilane derivative | Ciba SC Holding AG (CH) | 1998-04-22 | — | — | EP | disclosed |
| WO-1997002322-A1 | POLYSILANES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 1997-01-23 | — | — | WO | disclosed |
| EP-0434079-B1 | N,N'-hydrocarbylenebis(N-hals-substituted amic acid hydrazides) and their derivatives | ATOCHEM NORTH AMERICA (US) | 1995-09-20 | — | — | EP | disclosed |
| US-5386007-A | Siloxane copolymers containing alkenyl groups, their preparation and their use | WACKER-CHEMIE GMBH (DE) | 1995-01-31 | — | — | US | disclosed |
| US-5043372-A | Light stabilizers for polyolefins; reacting hydrazine with bis(half ester-half amide) | ATOCHEM NORTH AMERICA, INC. (US) | 1991-08-27 | — | — | US | disclosed |
| EP-0434079-A1 | N,N'-hydrocarbylenebis(N-hals-substituted amic acid hydrazides) and their derivatives | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1991-06-26 | — | — | EP | disclosed |