Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 16/20 | 0.54 |
| ▸ | HRH1 | P35367 | 14/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.54 |
| ▸ | DRD2 | P14416 | 3/20 | 0.41 |
| ▸ | DRD4 | P21917 | 3/20 | 0.41 |
| ▸ | DRD3 | P35462 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1929113 | 1.00 | CCR3 (0.54) | CCR3HRH1KCNH2DRD2DRD4 | |
| SCHEMBL1929589 | 0.91 | HRH1 (0.50) | CCR3HRH1KCNH2DRD2DRD4 | |
| SCHEMBL1929992 | 0.86 | HRH1 (0.59) | CCR3HRH1KCNH2 | |
| SCHEMBL1930131 | 0.86 | HRH1 (0.59) | CCR3HRH1KCNH2 | |
| SCHEMBL3283811 | 0.83 | HRH1 (0.60) | CCR3HRH1KCNH2DRD2DRD4 | |
| SCHEMBL3283807 | 0.83 | HRH1 (0.60) | CCR3HRH1KCNH2DRD2DRD4 | |
| SCHEMBL5655748 | 0.82 | CCR3 (0.47) | CCR3HRH1KCNH2 | |
| SCHEMBL3285920 | 0.81 | HRH1 (0.45) | CCR3HRH1KCNH2DRD2DRD4 | |
| SCHEMBL6651383 | 0.81 | HRH1 (0.45) | CCR3HRH1KCNH2DRD2DRD4 | |
| SCHEMBL1928549 | 0.81 | HRH1 (0.51) | CCR3HRH1KCNH2DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1713772-A1 | NOVEL PIPERIDINES AS CHEMOKINE MODULATORS (CCR) | AstraZeneca AB (SE) | 2006-10-25 | — | — | EP | disclosed |
| WO-2005073192-A1 | NOVEL PIPERIDINES AS CHEMOKINE MODULATORS (CCR) | ASTRAZENECA AB (SE) | 2005-08-11 | — | — | WO | disclosed |