Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | TTR | P02766 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15550392 | 1.00 | ALDH1A1 (0.53) | ALDH1A1TTRTSHR | |
| SCHEMBL2587435 | 1.00 | ALDH1A1 (0.53) | ALDH1A1TTRTSHR | |
| Tetrahydrofuran SCHEMBL28268799 | 1.00 | ALDH1A1 (0.53) | ALDH1A1TTRTSHR | |
| Tetrahydrothiophene SCHEMBL11806226 | 1.00 | ALDH1A1 (0.53) | ALDH1A1TTRTSHR | |
| Tetrahydrothiophene SCHEMBL15200771 | 1.00 | ALDH1A1 (0.53) | ALDH1A1TTRTSHR | |
| Tetrahydrofuran SCHEMBL1682253 | 0.97 | ALDH1A1 (0.57) | ALDH1A1TTRTSHR | |
| Tetrahydrofuran SCHEMBL7235639 | 0.97 | ALDH1A1 (0.57) | ALDH1A1TTRTSHR | |
| SCHEMBL10505667 | 0.93 | ALDH1A1 (0.53) | ALDH1A1TTRTSHR | |
| SCHEMBL14116483 | 0.93 | — | — | |
| SCHEMBL14583489 | 0.91 | ALDH1A1 (0.44) | ALDH1A1TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732567-A1 | USE OF A PHENOTHIAZINE DERIVATIVE FOR PREVENTING AND/OR TREATING HEARING LOSS | Societe de Conseils de Recherches et d'Applications Scientifiques (S.C.R.A.S) SAS (FR) | 2006-12-20 | — | — | EP | disclosed |
| WO-2005092345-A1 | USE OF A PHENOTHIAZINE DERIVATIVE FOR PREVENTING AND/OR TREATING HEARING LOSS | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2005-10-06 | — | — | WO | disclosed |