Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10585660 | 0.87 | TYR (0.35) | TYR | |
| SCHEMBL4831620 | 0.78 | CHRNA7 (0.41) | MEN1KMT2AACHEGRIA4ALDH1A1 | |
| SCHEMBL911297 | 0.78 | CHRNA7 (0.41) | MEN1KMT2AACHEGRIA4ALDH1A1 | |
| SCHEMBL96816 | 0.76 | ADRB2 (0.50) | MEN1KMT2AGAAHIF1ATDP1 | |
| SCHEMBL4145904 | 0.76 | MEN1 (0.38) | MEN1MAPTKMT2AACHEGRIA4 | |
| SCHEMBL28370167 | 0.76 | TYR (0.43) | MEN1MAPTKMT2AACHEGRIA4 | |
| SCHEMBL6141138 | 0.76 | IDO1 (0.38) | ACHEALDH1A1GAAHTTTDP1 | |
| SCHEMBL582044 | 0.76 | ESR1 (0.54) | MEN1MAPTKMT2AALDH1A1HIF1A | |
| SCHEMBL3151083 | 0.75 | MIF (0.41) | ALDH1A1HIF1ALMNA | |
| SCHEMBL8711629 | 0.75 | MIF (0.41) | ALDH1A1HIF1ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1656390-A2 | COMPOSITIONS OF LIPOPEPTIDE ANTIBIOTIC DERIVATIVES AND METHODS OF USE THEREOF | MIGENIX INC. (CA) | 2006-05-17 | — | — | EP | claimed |
| WO-2005000878-A2 | COMPOSITIONS OF LIPOPEPTIDE ANTIBIOTIC DERIVATIVES AND METHODS OF USE THEREOF | MIGENIX INC. (CA) | 2005-01-06 | — | — | WO | claimed |
| EP-0560267-B1 | Isosteric antiherpes peptide derivatives | BOEHRINGER INGELHEIM CA LTD (CA) | 1998-08-19 | — | — | EP | claimed |
| EP-0767671-A1 | METHOD OF COMBATING ACYCLOVIR-RESISTANT HERPES SIMPLEX VIRAL INFECTIONS | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 1997-04-16 | — | — | EP | claimed |
| US-5574015-A | Isosteric antiherpes peptide derivatives | BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) | 1996-11-12 | — | — | US | claimed |
| CN-1096300-A | Isosteric antiherpes peptide derivatives | BIO MEGA BOEHRINGER INGELHEIM (CA) | 1994-12-14 | — | — | CN | claimed |
| WO-1994025046-A1 | METHOD OF COMBATING ACYCLOVIR-RESISTANT HERPES SIMPLEX VIRAL INFECTIONS | BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) | 1994-11-10 | — | — | WO | claimed |
| WO-1993018056-A1 | ISOSTERIC ANTIHERPES PEPTIDE DERIVATIVES | BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) | 1993-09-16 | — | — | WO | claimed |
| EP-0560267-A1 | Isosteric antiherpes peptide derivatives | BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) | 1993-09-15 | — | — | EP | claimed |
| EP-0493770-A2 | Antiherpes compositions | BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) | 1992-07-08 | — | — | EP | claimed |
| CN-113766954-A | Camptothecin derivatives | 伊缪诺金公司 | 2021-12-07 | — | — | CN | disclosed |
| CN-109843334-A | The targeted delivery of nicotinamide adenine dinucleotide remedial pathway inhibitor | 西雅图基因公司 | 2019-06-04 | — | — | CN | disclosed |
| CN-103533957-B | The humanized antibody of anti-LIV-1 and the purposes in treatment cancer thereof | 西雅图遗传学公司 | 2016-06-22 | — | — | CN | disclosed |
| CN-105517577-A | Enzymatic conjugation of polypeptides | INNATE PHARMA | 2016-04-20 | — | — | CN | disclosed |
| CN-103533957-A | Humanized antibodies to LIV-1 and use of same to treat cancer | SEATTLE GENETICS INC | 2014-01-22 | — | — | CN | disclosed |
| US-5574015-A | Isosteric antiherpes peptide derivatives | BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) | 1996-11-12 | — | — | US | disclosed |
| US-5552384-A | Antiherpes compositions and method of use | BIO-MEGA BOEHRINGER INGELHEIM RESEARCH INC. (CA) | 1996-09-03 | — | — | US | disclosed |
| WO-1993018056-A1 | ISOSTERIC ANTIHERPES PEPTIDE DERIVATIVES | BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) | 1993-09-16 | — | — | WO | disclosed |
| EP-0560267-A1 | Isosteric antiherpes peptide derivatives | BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) | 1993-09-15 | — | — | EP | disclosed |
| EP-0493770-A2 | Antiherpes compositions | BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) | 1992-07-08 | — | — | EP | disclosed |