Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | CTSD | P07339 | 1/20 | 0.48 |
| ▸ | CTSE | P14091 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5987868 | 1.00 | REN (0.53) | RENCYP3A4CTSDCTSE | |
| SCHEMBL5987872 | 1.00 | REN (0.53) | RENCYP3A4CTSDCTSE | |
| SCHEMBL5466075 | 0.95 | REN (0.52) | RENCYP3A4CTSDCTSE | |
| SCHEMBL5466070 | 0.95 | REN (0.52) | RENCYP3A4CTSDCTSE | |
| SCHEMBL5466081 | 0.95 | REN (0.52) | RENCYP3A4CTSDCTSE | |
| SCHEMBL8231645 | 0.91 | REN (0.51) | RENCYP3A4CTSDCTSE | |
| SCHEMBL8225999 | 0.90 | REN (0.51) | RENCYP3A4CTSDCTSE | |
| SCHEMBL13232845 | 0.89 | REN (0.49) | RENCYP3A4CTSDCTSE | |
| SCHEMBL13232843 | 0.88 | REN (0.49) | RENCYP3A4CTSDCTSE | |
| SCHEMBL5470619 | 0.87 | REN (0.52) | RENCYP3A4CTSDCTSE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1692132-A2 | AZABICYCLOOCTENE AND OTHER TETRAHYDROPYRIDINE DERIVATIVES WITH A NEW SIDE-CHAIN | Actelion Pharmaceuticals Ltd. (CH) | 2006-08-23 | — | — | EP | disclosed |
| WO-2005054244-A2 | AZABICYCLOOCTENE AND OTHER TETRAHYDROPYRIDINE DERIVATIVES WITH A NEW SIDE-CHAIN | ACTELION PHARMACEUTICALS LTD (CH) | 2005-06-16 | — | — | WO | disclosed |