Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 15/20 | 0.50 |
| ▸ | PGR | P06401 | 2/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1379986 | 0.89 | AR (0.50) | ARPGRS1PR1RXRARXRB | |
| SCHEMBL5191017 | 0.88 | AR (0.47) | ARPGRS1PR1RXRARXRB | |
| SCHEMBL3291502 | 0.87 | AR (0.50) | ARPGRS1PR1RXRARXRB | |
| SCHEMBL3289697 | 0.85 | AR (0.55) | ARPGRS1PR1RXRARXRB | |
| SCHEMBL3289642 | 0.84 | AR (0.54) | ARPGRS1PR1RXRARXRB | |
| SCHEMBL13326442 | 0.83 | AR (0.53) | ARPGRS1PR1RXRARXRB | |
| SCHEMBL5193065 | 0.83 | AR (0.44) | ARPGR | |
| SCHEMBL1378445 | 0.80 | AR (0.44) | ARPGR | |
| SCHEMBL13070686 | 0.78 | RORC (0.48) | ARPGR | |
| SCHEMBL3054642 | 0.78 | AR (0.59) | ARPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1725522-A1 | ANILINE DERIVATIVES AS SELECTIVE ANDROGEN RECEPTOR MODULATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2006-11-29 | — | — | EP | disclosed |
| WO-2005085185-A1 | ANILINE DERIVATIVES AS SELECTIVE ANDROGEN RECEPTOR MODULATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-09-15 | — | — | WO | disclosed |