Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 15/20 | 0.38 |
| ▸ | PPARD | Q03181 | 15/20 | 0.38 |
| ▸ | PPARA | Q07869 | 13/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 2/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5989715 | 1.00 | PPARG (0.38) | PPARGPPARDPPARACYP1A2CYP2A6 | |
| SCHEMBL5989709 | 1.00 | PPARG (0.38) | PPARGPPARDPPARACYP1A2CYP2A6 | |
| SCHEMBL6054881 | 0.88 | PPARG (0.33) | PPARGPPARDPPARACYP1A2CYP2A6 | |
| SCHEMBL5991756 | 0.82 | PPARG (0.38) | PPARGPPARDPPARA | |
| SCHEMBL5989015 | 0.82 | PPARG (0.38) | PPARGPPARDPPARA | |
| SCHEMBL5990443 | 0.75 | PPARG (0.57) | PPARGPPARDPPARA | |
| SCHEMBL5990452 | 0.75 | PPARG (0.57) | PPARGPPARDPPARA | |
| SCHEMBL5991677 | 0.75 | PPARG (0.72) | PPARGPPARDPPARA | |
| SCHEMBL5996707 | 0.75 | PPARG (0.57) | PPARGPPARDPPARA | |
| SCHEMBL5992147 | 0.75 | PPARG (0.72) | PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060257987-A1 | Ppar modulators | ELI LILLY AND COMPANY | 2006-11-16 | — | — | US | disclosed |
| EP-1660428-A1 | PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005019151-A1 | PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-03-03 | — | — | WO | disclosed |