Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 17/20 | 0.68 |
| ▸ | PPARA | Q07869 | 16/20 | 0.68 |
| ▸ | PPARD | Q03181 | 16/20 | 0.68 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.43 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5990058 | 1.00 | PPARG (0.68) | PPARGPPARAPPARDLTB4RLTB4R2 | |
| SCHEMBL5988824 | 0.91 | PPARG (0.67) | PPARGPPARAPPARD | |
| SCHEMBL5988827 | 0.91 | PPARG (0.67) | PPARGPPARAPPARD | |
| SCHEMBL5411425 | 0.90 | PPARG (0.77) | PPARGPPARAPPARD | |
| SCHEMBL5411420 | 0.90 | PPARG (0.77) | PPARGPPARAPPARD | |
| SCHEMBL5989516 | 0.89 | PPARG (0.65) | PPARGPPARAPPARD | |
| SCHEMBL5989519 | 0.89 | PPARG (0.65) | PPARGPPARAPPARD | |
| SCHEMBL5991963 | 0.88 | PPARA (0.59) | PPARGPPARAPPARD | |
| SCHEMBL5991958 | 0.88 | PPARA (0.59) | PPARGPPARAPPARD | |
| SCHEMBL5990814 | 0.85 | PPARA (0.64) | PPARGPPARAPPARDACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060257987-A1 | Ppar modulators | ELI LILLY AND COMPANY | 2006-11-16 | — | — | US | claimed |
| US-20060257987-A1 | Ppar modulators | ELI LILLY AND COMPANY | 2006-11-16 | — | — | US | disclosed |
| EP-1660428-A1 | PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005019151-A1 | PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-03-03 | — | — | WO | disclosed |