Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 19/20 | 0.64 |
| ▸ | PPARD | Q03181 | 16/20 | 0.64 |
| ▸ | PPARG | P37231 | 15/20 | 0.64 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5990821 | 1.00 | PPARA (0.64) | PPARAPPARDPPARGACACB | |
| SCHEMBL5990052 | 0.85 | PPARG (0.68) | PPARAPPARDPPARGACACB | |
| SCHEMBL5990058 | 0.85 | PPARG (0.68) | PPARAPPARDPPARGACACB | |
| SCHEMBL5411425 | 0.84 | PPARG (0.77) | PPARAPPARDPPARG | |
| SCHEMBL5411420 | 0.84 | PPARG (0.77) | PPARAPPARDPPARG | |
| SCHEMBL5990252 | 0.80 | PPARA (0.64) | PPARAPPARDPPARG | |
| SCHEMBL5990249 | 0.80 | PPARA (0.64) | PPARAPPARDPPARG | |
| SCHEMBL5988827 | 0.79 | PPARG (0.67) | PPARAPPARDPPARG | |
| SCHEMBL5988824 | 0.79 | PPARG (0.67) | PPARAPPARDPPARG | |
| SCHEMBL5990927 | 0.78 | PPARG (0.59) | PPARAPPARDPPARGACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060257987-A1 | Ppar modulators | ELI LILLY AND COMPANY | 2006-11-16 | — | — | US | claimed |
| US-20060257987-A1 | Ppar modulators | ELI LILLY AND COMPANY | 2006-11-16 | — | — | US | disclosed |
| EP-1660428-A1 | PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005019151-A1 | PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-03-03 | — | — | WO | disclosed |