Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 4/20 | 0.38 |
| ▸ | PPARD | Q03181 | 3/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5990644 | 1.00 | PPARA (0.38) | PPARAPPARDFFAR1FFAR4PPARG | |
| SCHEMBL8156359 | 0.81 | MCHR1 (0.47) | PPARAPPARDFFAR1FFAR4MCHR1 | |
| SCHEMBL5992014 | 0.80 | SLC6A4 (0.40) | PPARAPPARDFFAR1FFAR4PPARG | |
| SCHEMBL5992016 | 0.80 | SLC6A4 (0.40) | PPARAPPARDFFAR1FFAR4PPARG | |
| SCHEMBL8163202 | 0.80 | FFAR1 (0.39) | PPARAPPARDFFAR1FFAR4MCHR1 | |
| SCHEMBL8148399 | 0.78 | S1PR1 (0.46) | ALDH1A1POLBGAATHRBSMN1; SMN2 | |
| SCHEMBL19616709 | 0.76 | MAPT (0.43) | MCHR1ALDH1A1POLBGAATHRB | |
| SCHEMBL29493403 | 0.76 | MAPT (0.43) | MCHR1ALDH1A1POLBGAATHRB | |
| SCHEMBL8160442 | 0.75 | GRM7 (0.40) | ALDH1A1POLBGAATHRB | |
| SCHEMBL7651507 | 0.75 | KDM4E (0.46) | ALDH1A1POLBGAATHRBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060257987-A1 | Ppar modulators | ELI LILLY AND COMPANY | 2006-11-16 | — | — | US | disclosed |