Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 3/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5992014 | 1.00 | SLC6A4 (0.40) | SLC6A4SLC6A3PPARAPPARGPPARD | |
| SCHEMBL5990639 | 0.80 | PPARA (0.38) | PPARAPPARGPPARDMCHR1FFAR1 | |
| SCHEMBL5990644 | 0.80 | PPARA (0.38) | PPARAPPARGPPARDMCHR1FFAR1 | |
| SCHEMBL8163202 | 0.74 | FFAR1 (0.39) | PPARAPPARDMCHR1FFAR1FFAR4 | |
| SCHEMBL8156359 | 0.73 | MCHR1 (0.47) | PPARAPPARDMCHR1FFAR1FFAR4 | |
| SCHEMBL8148399 | 0.72 | S1PR1 (0.46) | TACR1 | |
| SCHEMBL19616709 | 0.70 | MAPT (0.43) | SLC6A4SLC6A3MCHR1CHRM5 | |
| SCHEMBL9721831 | 0.70 | TDP1 (0.41) | — | |
| SCHEMBL29493403 | 0.70 | MAPT (0.43) | SLC6A4SLC6A3MCHR1CHRM5 | |
| SCHEMBL5992130 | 0.70 | PPARG (0.53) | SLC6A4SLC6A3PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060257987-A1 | Ppar modulators | ELI LILLY AND COMPANY | 2006-11-16 | — | — | US | disclosed |